Animal Peptidomics Analysis Service

Animal peptidomics refers to the systematic identification, quantification, and functional prediction of endogenous short peptides in animals through high-throughput techniques such as mass spectrometry. This field of research covers a wide range of biological sample types, including serum, tissue, urine, cerebrospinal fluid, and more. By profiling the expression and dynamic changes of peptides, animal peptidomics helps uncover biomarkers under physiological or pathological conditions and provides a solid foundation for the discovery and development of novel functional peptides.

 

As a CRO dedicated to multi-omics research, MtoZ Biolabs has built a comprehensive animal peptidomics analysis platform that integrates sample preparation, mass spectrometry, and bioinformatics. Equipped with high-resolution MS systems such as Orbitrap Fusion Lumos and Q Exactive HF, and customized data analysis pipelines, we deliver high-quality, reproducible Animal Peptidomics Analysis Service to support peptide drug discovery, biomarker identification, and animal model research for academic and industrial clients.

 

Services at MtoZ Biolabs

MtoZ Biolabs offers a full-service pipeline for Animal Peptidomics Analysis Service, from sample preprocessing and low-molecular-weight peptide enrichment to high-resolution MS detection and in-depth data analysis. Leveraging our advanced platform and experienced team, we provide peptide identification, quantification, targeted functional peptide screening, and customized project solutions to help researchers comprehensively explore peptide expression patterns and biological functions in animal systems, driving discoveries in peptide biology, mechanism studies, and therapeutic development.

 

Analysis Workflow

MtoZ Biolabs follows a standardized workflow for animal peptidomics analysis service:

 

1. Sample Preprocessing

Assess sample quality and apply deproteinization, desalting, and filtration strategies to enrich low-molecular-weight peptides.

 

2. Mass Spectrometry Analysis

Perform peptide scans and MS/MS fragmentation using sensitive LC-MS/MS platforms.

 

3. Data Processing

Match peptides using professional databases such as UniProt and PeptideAtlas.

 

4. Functional Annotation

Conduct differential expression analysis, GO/KEGG pathway annotation, and functional insights.

 

5. Reporting

Provide original MS data, interpreted results, annotation summaries, and visualized charts.

 



Service Advantages

1. High-resolution mass spectrometry platform

Utilizing state-of-the-art instruments like Orbitrap Fusion Lumos and Q Exactive HF, we ensure high sensitivity and accuracy in peptide detection, even in complex biological matrices.

 

2. Broad sample compatibility

We support various sample types and animal models (mouse, rat, pig, monkey, etc.), covering diverse biological matrices such as serum, tissues, cerebrospinal fluid, and urine—ideal for neuroscience, immunology, metabolic disease, and more.

 

3. Comprehensive bioinformatics capabilities

Backed by curated peptide function databases and integration with GO/KEGG annotation systems, our pipeline supports peptide classification, PTM prediction, and pathway enrichment, yielding meaningful biological insights.

 

4. Flexible customization

From exploratory screening to targeted validation, our Animal Peptidomics Analysis Service supports various research needs, including peptide drug discovery, functional studies, and efficacy evaluation.

 

5. Rigorous quality control

Each step of the process includes built-in QC checkpoints, ensuring reproducibility and reliability of results, which are suitable for publication and regulatory use.

 

Applications

1. Functional peptide discovery and development: Mining endogenous bioactive peptides for applications such as antimicrobial, immunomodulatory, and metabolic regulatory peptides.

2. Mechanistic studies using animal disease models: Comparing peptide profiles across experimental groups to uncover disease-associated biomarkers and pathways.

3. Neuropeptide and behavioral studies: Investigating changes in neuropeptides from brain tissue to understand emotion, cognition, and nervous system function.

4. Food and nutritional science: Analyzing bioactive peptides in animal-derived food products (milk, meat, eggs) to assess nutritional and functional properties.

5. Toxicology and pharmacodynamic evaluation: Profiling peptide changes in response to drug interventions to evaluate mechanism of action and physiological response.

 

FAQs

Q1: How is data reliability ensured?

A1: We implement rigorous QC measures including replicate runs, blanks, standards, and internal controls to ensure data accuracy, reproducibility, and reliability.

 

Q2: What is the typical turnaround time for Animal Peptidomics Analysis Service?

A2: For standard projects with qualified samples, the typical turnaround time is 3–4 weeks. The timeline may vary depending on sample quantity, quantification strategy (e.g., TMT/iTRAQ), and analysis complexity. For advanced tasks such as functional peptide screening or extensive bioinformatics, additional time may be required. A detailed project timeline will be provided prior to initiation.

 

Sample Submission Suggestions

 

Sample Type	Recommended Amount (Total Protein)	Notes
Serum/Plasma	≥ 100 µL	Avoid hemolysis; use anticoagulant-free tubes
Tissue Samples	≥ 50 mg	Frozen sections or liquid nitrogen grinding recommended
Urine	≥ 500 µL	Midstream morning urine preferred
CSF/Others	≥ 100 µL	Store frozen; avoid repeated freeze-thaw

 

To maintain sample integrity, please avoid multiple freeze-thaw cycles. Dry ice shipping is recommended. Contact us for detailed preparation instructions.

 

Deliverables

1. Identified peptide information (sequence, length, mass, source protein, etc.)

2. Quantitative analysis report (expression levels, fold change, p-values)

3. Functional annotation (GO/KEGG pathways, functional categories)

4. Visual summaries (heatmaps, volcano plots, PCA, enrichment charts)

5. Raw MS data files (.raw, .mzML, etc.)

6. Final project report in PDF format

 

Peptides play critical roles as functional effectors and molecular messengers in biological systems. Their importance in animal experiments, therapeutic research, and mechanistic studies continues to grow. MtoZ Biolabs provides high-quality, end-to-end Animal Peptidomics Analysis Services with expert support, reliable workflows, and tailored solutions. Contact our scientific team to start uncovering the hidden potential of peptides in your research today.