Xanthurenic Acid Analysis Service

    Xanthurenic acid (XA) is a metabolic byproduct of tryptophan degradation along the kynurenine pathway, which plays an important role in various biological processes. It is known to be involved in several physiological functions, including neurotransmission and immune regulation, making it a subject of increasing interest in both basic research and clinical studies.

     

    Xanthurenic acid has been associated with several pathological conditions, particularly those related to tryptophan metabolism disorders, such as neurodegenerative diseases, diabetes, and immune dysfunctions. Elevated levels of xanthurenic acid have been linked to altered neurotransmitter balance, which may contribute to neurological diseases like schizophrenia and depression. Additionally, recent studies suggest that XA may act as a ligand for specific receptors in parasitic infections, such as malaria, playing a crucial role in disease progression. These findings underscore the importance of analyzing XA levels for better understanding its potential as a biomarker in disease diagnostics and therapeutic monitoring.

     

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    Figure 1. The Structure of Xanthurenic Acid

     

    MtoZ Biolabs specializes in providing comprehensive xanthurenic acid analysis service. We employ ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), a highly sensitive and accurate method, to detect and quantify XA in various biological samples.

     

    Analysis Workflow

     

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    Service Advantages

    • Extensive expertise in handling various biological samples and extracting metabolites.
    • State-of-the-art mass spectrometry platforms: UPLC-MS, GC-MS, MRM method.
    • Strict quality control to ensure reliable results.
    • Comprehensive statistical and bioinformatics analysis.
    • Personalized service to meet various research needs.

     

    Applications

    Our XA analysis service can be applied in various research fields, including but not limited to:

    • Biomarker discovery for metabolic disorders
    • Therapeutic efficacy evaluation
    • Disease diagnosis and prognosis

     

    Sample Submission Requirements

     

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    • Samples should be stored at -80℃ and shipped with dry ice.
    • We recommend providing at least 3 samples of similar conditions for each type of sample.
    • Please provide details on sample collection and handling.
    • Other sample types, please contact us for more details.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Xanthurenic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    MtoZ Biolabs is committed to providing high-quality and reliable services to assist your XA research. Please feel free to contact us for more information about our XA analysis service.

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