Volatile Metabolomics Analysis Service

    Volatile metabolomics is the scientific study of volatile organic compounds (VOCs) within biological samples. These volatile metabolites, typically low-molecular-weight compounds generated through metabolic processes, possess the ability to evaporate and diffuse into the surrounding environment. Due to their presence both within and outside of organisms, volatile metabolites serve as key indicators of metabolic activity changes. This makes them invaluable across various fields, including food quality control, environmental monitoring, disease diagnosis, and microbial research. By utilizing volatile metabolomics analysis, researchers can accurately profile metabolite types, investigate metabolic pathways, and identify potential biomarkers.

     

    MtoZ Biolabs offers Volatile Metabolomics Analysis Service through advanced mass spectrometry platforms. Our comprehensive services span the entire workflow, from sample preparation to high-precision gas chromatography-mass spectrometry (GC-MS) and sophisticated data analysis. We help clients uncover the functional roles of volatile metabolites in biological systems, furthering advancements in disease mechanism studies, food safety evaluations, and environmental assessments.

     

    Analysis Workflow

     1846103630945046528-TheWorkflowofVolatileMetabolomicsAnalysis.jpg

    Yang, Y. Q. et al. Food Chem. 2024.

     

    Service Advantages

    1. Extensive Metabolomic Coverage

    MtoZ Biolabs offers both volatile metabolomics using the headspace GC-MS platform and non-volatile metabolite analysis through LC-MS, ensuring comprehensive profiling of metabolite species with the highest data accuracy.

     

    2. Exceptional Sensitivity and Precision

    Our GC-MS and LC-MS platforms deliver ultra-sensitive detection of low-abundance metabolites while maintaining exceptional accuracy and reproducibility across all datasets.

     

    3. Tailored Analytical Solutions

    We provide customized metabolomics solutions that cater to the specific needs of each research project, ensuring flexibility and depth in analytical approaches.

     

    4. Streamlined Workflows

    From sample preparation to data interpretation, we offer streamlined analytical workflows designed to deliver detailed and accurate reports within short turnaround times.

     

    Sample Submission Requirements

    1. Sample Types

    Various sample types are accepted, including serum, urine, exhaled breath, and food samples.

     

    2. Sample Volume

    At least 200 μL of liquid sample or 200 mg of solid sample.

     

    3. Sample Preservation

    Samples must be sealed and stored at low temperatures to prevent the loss of volatile metabolites. For transportation, dry ice or liquid nitrogen is recommended.

     

    Applications

    • Food Safety and Quality Control: Analyze volatile and non-volatile metabolites in food products to assess freshness, flavor composition, and overall quality control.
    • Environmental Monitoring: Detect both volatile organic compounds (VOCs) and non-volatile metabolites in environmental samples to evaluate pollution levels and implement early environmental risk assessments.
    • Disease Diagnosis: Through volatile and non-volatile metabolite profiling in exhaled breath and body fluids, identify biomarkers for early diagnosis of diseases such as lung cancer and liver disorders.
    • Drug Metabolism Research: Evaluate the metabolic pathways of drugs by analyzing volatile and non-volatile metabolites, offering insights into drug metabolism and its biological effects.

     

    Deliverables

    What Could be Included in the Report?

    1. Comprehensive Experimental details

    2. Materials, Instruments, and Methods

    3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)

    4. Data Analysis, Preprocessing, and Estimation (project-dependent)

    5. Bioinformatics Analysis

    6. Raw Data Files

     

    As a premier in metabolomics research services, MtoZ Biolabs provides not only advanced volatile metabolomics solutions but also comprehensive non-volatile metabolomics services. By leveraging innovative technologies and highly efficient workflows, we empower researchers to achieve groundbreaking results in both scientific research and applied industries. For more details or to discuss customized solutions, please contact us for a consultation.

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