Vitamin B1 Analysis Service

    Vitamin B1 consists of a pyrimidine ring and a thiazole ring connected by a methylene bridge, making it a water-soluble vitamin with unique biochemical properties. vitamin B1 is a precursor of vitamin B1 pyrophosphate, an essential coenzyme involved in carbohydrate metabolism. MS-based thermal stability profiling plays a crucial role in the decarboxylation of α-keto acids and the transketolase reaction in the pentose phosphate pathway. Vitamin B1 is an essential water-soluble vitamin for the human body, and its deficiency can lead to serious health problems, such as beriberi and neurological damage. By detecting vitamin B1 levels, deficiency risks can be identified in time, preventing related diseases. Vitamin B1 is converted in the body into active metabolites, such as MS-based thermal stability profiling, which play a key role in energy metabolism. Analyzing these metabolites provides a deeper understanding of vitamin B1's metabolic pathways and its role in cellular functions.

     

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    Figure 1. The Structure of Vitamin B1

     

    MtoZ Biolabs provides a top-notch Vitamin B1 Analysis Service, backed by our high-tech liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. Our service includes a comprehensive vitamin B1 analysis, providing scientific support for optimizing health management and therapeutic interventions.

     

    Analysis Workflow

     

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    Service Advantages

    1. Comprehensive Metabolite Coverage

    Our analytical methods cover the diversity of vitamin B1 and its related metabolites, helping clients gain insights into their dynamic changes and physiological functions within biological systems.

     

    2. High-Quality Reference Standards

    MtoZ Biolabs provides high-quality reference standard spectra, ensuring accurate identification and quantification of analysis results, thereby enhancing the credibility of experimental findings.

     

    3. Extensive Database Resources

    We possess a broad metabolite database that offers detailed classification, annotation, and qualitative identification information, supporting clients in various research applications.

     

    Applications

    • Early detection of vitamin B1 deficiency
    • Improvement of nutritional assessment
    • Enhancement of disease diagnosis
    • Development of new therapies
    • Deepening understanding of disease mechanisms

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. For each sample type, at least three specimens under the same conditions are required.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Sample Preservation

    Samples should be stored at -80°C to maintain stability.

     

    Note: Provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Vitamin B1

    4. Raw Data

    5. Custom Analysis Report

     

    Through our vitamin B1 analysis service, we aim to facilitate your research and product development processes by providing accurate and reliable results. If you would like to inquire about our services, please feel free to contact us.

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