Urocanic Acid Analysis Service

    Urocanic acid is a naturally occurring compound produced in the body through the deamination of histidine by histidase in the liver or skin. Its structure consists of an imidazole ring with a double bond, making it a significant natural moisturizing factor in the skin with the ability to absorb ultraviolet (UV) radiation. Due to this property, urocanic acid plays an important role in skin photoprotection and sun defense.

     

    In tumor cells, the metabolism of urocanic acid may undergo changes, and alterations in its levels and metabolic processes could be associated with the occurrence, development, and malignant transformation of cancer. In certain types of skin cancer, changes in the levels and metabolites of urocanic acid may serve as biomarkers for tumor activity and therapeutic efficacy. Therefore, measuring the levels of urocanic acid and its metabolites can be used to assess tumor activity and treatment effectiveness. Additionally, because urocanic acid may also be produced by the metabolism of skin microbiota, elevated levels may indicate local infection or inflammation. Monitoring its metabolites can help evaluate the severity of bacterial infection and the intensity of the inflammatory response.

     

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    Figure 1. The Structure of Urocanic Acid

     

    MtoZ Biolabs offers a state-of-the-art Urocanic Acid Analysis Service, powered by our premium liquid chromatography-mass spectrometry (LC-MS) platform and proficient metabolomics team. Our service provides a comprehensive urocanic acid analysis, ensuring optimal sensitivity and accuracy.

     

    Analysis Workflow

     

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    Service Advantages

    • High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.
    • Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.
    • Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.
    • Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

     

    Applications

    • Qualitative analysis of urocanic acid metabolites
    • Quantitative analysis of urocanic acid concentration
    • Provide a scientific basis for improving research and product development

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Sample Preservation

    Store at -80°C to maintain stability.

     

    Note: Provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Urocanic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    By offering our Urocanic Acid Analysis Service, we aim to facilitate your research and product development by providing precise and trustworthy results.

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