Untargeted Metabolomics
- Comprehensive Metabolite Coverage: Capable of analyzing over 95% of known metabolic pathways' small molecule metabolites.
- Exceptional Sensitivity and Precision: Utilizes LC-MS technology to detect minute quantities of metabolites across a variety of biological samples efficiently.
- Versatile Sample Compatibility: Supports a wide array of sample types including blood, urine, tissues, and cells.
- Animal tissues: ≥ 100 mg
- Plant tissue: ≥ 200 mg
- Cells: ≥ 1×10^7 cells
- Microbes: ≥ 200 µL
- Serum/plasma ≥ 200 μL
- Urine: ≥ 2 mL
Untargeted Metabolomics is a robust analytical technique designed for a comprehensive exploration of all measurable metabolites without predefined hypotheses. This method enables a thorough examination of metabolomic profile changes within biological samples, facilitating an understanding of biochemical functions during both normal and diseased states. Our untargeted metabolomics services leverage cutting-edge analytical technologies to identify both known and novel metabolites, offering fresh scientific insights for disease research and biopharmaceutical advancements.
MtoZ Biolabs conducts untargeted metabolomics analyses using state-of-the-art liquid chromatography-mass spectrometry (LC-MS). This technique meticulously analyzes complex metabolite mixtures, including organic acids, amino acids, and lipids, all crucial for comprehensive metabolic profiling.
Analysis Workflow
Zeki, Ö. C. et al. J. Pharm. Biomed, 2020.
Figure 1. Untargeted Metabolomics Analysis Workflow
Data Analysis
Services at MtoZ Biolabs
Lipidomics
Plant Metabolomics
Animal Metabolomics
Microbial Metabolomics
Exosome Metabolomics
Service Advantages
Sample Submission Requirements
Sample Types
Sample Volume
Please contact our technical team for more detailed requests for samples.
Applications
1. Disease Mechanism Research: Investigates metabolic alterations associated with specific diseases, uncovering underlying disease mechanisms.
2. Drug Development: Evaluates drugs' metabolic effects to inform the design and optimization of dosages.
3. Precision Medicine: Utilizes metabolic biomarkers for diagnosing and evaluating treatment efficacy, enhancing treatment customization and accuracy.
4. Environmental Impact Studies: Examines the influence of environmental factors on metabolic activities within organisms.
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