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    Trans-Vaccenic Acid Analysis Service

      Trans-vaccenic acid (C18:1 trans-11) is a monounsaturated trans-fatty acid, consisting of 18 carbon atoms and a double bond located at the 11th carbon position. Its structural formula is CH₃(CH₂)₅CH=CH(CH₂)₇COOH, with the double bond in a trans configuration. As a long-chain fatty acid, trans-vaccenic acid typically exists as an oily liquid with a low melting point and high oxidative stability. It is primarily found in the adipose tissue, dairy products, and meat of ruminant animals, particularly in high concentrations in milk and beef. 

       

      In the body, trans-vaccenic acid can be partially converted into conjugated linoleic acid (CLA), which is believed to have multiple health benefits, such as anti-cancer, anti-obesity, and immune-modulating effects. Therefore, trans-vaccenic acid is not only an important metabolic product but also serves as a precursor to CLA, making it a subject of study in functional foods. In industrial applications, trans-vaccenic acid and its derivatives can be used in the synthesis of cosmetics, pharmaceuticals, and biomaterials. In biological research, it is also a key compound in studies on lipid metabolism, fatty acid metabolic pathways, and the effects of dietary fats on health.

       

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      Figure 1. The Structure of Trans-Vaccenic Acid

       

      MtoZ Biolabs is proud to offer a comprehensive Trans-Vaccenic Acid Analysis Service, utilizing our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and an experienced metabolomics team. Our service ensures a thorough analysis of trans-vaccenic acid, promising high sensitivity and precision.

       

      Analysis Workflow 

       

      1836280377376362496-WorkflowofRetinoicAcidAnalysisService.PNG

       

      Service Advantages

      1. High Sensitivity and Accuracy

      MtoZ Biolabs' liquid chromatography-mass spectrometry (LC-MS) analysis platform can detect extremely low concentrations of trans-vaccenic acid and its metabolites, which is particularly important for studying their minute changes in cells, tissues, and bodily fluids.  

       

      2. High Specificity

      By optimizing chromatographic separation conditions and mass spectrometry detection parameters, trans-vaccenic acid and its various metabolites can be effectively distinguished in complex biological samples, minimizing interference from other endogenous or exogenous substances and improving detection specificity.  

       

      3. Customized Analysis

      Tailored analytical solutions can be designed according to research needs, providing personalized solutions for different biological samples and target molecules.

       

      Applications

      • Potential in the development of new disease biomarkers
      • Aiding in disease diagnosis
      • Accelerating the discovery of innovative therapeutic solutions
      • Providing new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological material. A minimum of 3 samples of the same type should be submitted for each analysis.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C for stability.

       

      Note: Please provide detailed information on sample collection and handling methods.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Trans-vaccenic Acid

      4. Raw Data

      5. Custom Analysis Report

       

      Our Trans-vaccenic Acid Analysis Service strives to support your research and product development processes by delivering accurate and reliable results. If you are interested in our related services, please feel free to contact us.

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