Thymine Analysis Service
- Identifying new disease biomarkers
- Improving disease diagnosis
- Accelerating the development of innovative therapeutics
- Gaining deeper understanding of disease mechanisms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/Plasma ≥ 200 μL
- Urine ≥ 2 mL
Thymine is a pyrimidine nucleobase with a single-ring structure, featuring a keto group at the 4th position and a methyl group at the 5th position. Thymine is an essential component of DNA, and changes in its content and metabolites directly reflect the activity of DNA synthesis and repair. By detecting thymine and its metabolites, the proliferation status of cells and DNA damage repair capacity can be assessed, which is of great significance for the diagnosis and treatment of diseases such as cancer and aplastic anemia. Thymine can be reduced to dihydrothymine under the action of dihydropyrimidine dehydrogenase, an important intermediate in thymine degradation metabolism. Deficiency in dihydropyrimidine dehydrogenase can lead to abnormal pyrimidine metabolism, causing neurological and digestive system disorders. Detecting the levels of thymine and its metabolites helps diagnose these metabolic disorders and monitor disease progression.
Figure 1. The Structure of Thymine
MtoZ Biolabs is proud to introduce our top-tier Thymine Analysis Service. Leveraging our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and expert metabolomics team, we deliver comprehensive analysis of thymineIt, providing important scientific evidence for studying DNA metabolism, assessing genetic stability, optimizing drug therapy, and diagnosing genetic disorders, and offering precise data support for health management and personalized treatment.
Analysis Workflow
Service Advantages
1. Comprehensive Metabolite Coverage
Our analytical methods cover the diversity of thiamine and its related metabolites, helping clients gain insights into their dynamic changes and physiological functions within biological systems.
2. High-Quality Reference Standards
MtoZ Biolabs provides high-quality reference standard spectra, ensuring accurate identification and quantification of analysis results, thereby enhancing the credibility of experimental findings.
3. Extensive Database Resources
We possess a broad metabolite database that offers detailed classification, annotation, and qualitative identification information, supporting clients in various research applications.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples are all acceptable. Please submit more than 3 replicates per sample.
2. Sample Volume
3. Sample Preservation
To maintain stability, samples must be stored at -80°C.
Note: Please provide detailed information on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Thymine
4. Raw Data
5. Custom Analysis Report
Through our Thymine Analysis Service, we dedicate ourselves to supporting your research and product development by ensuring accurate and reliable results. If you would like to inquire about our services, please feel free to contact us.
How to order?
