Thioguanine Analysis Service
- Extensive experience in various biological sample preparation techniques
- Professional standard operating procedure
- State-of-the-art facilities and equipment for precise analysis
- Expert team with extensive experience in metabolomics
- Comprehensive data analysis
- Excellent customer service and after-service support
- Improving disease diagnosis, particularly in cancer research.
- Accelerating the discovery of new therapeutic strategies.
- Unravelling new insights into disease mechanisms, specifically in the field of oncology.
- Enhancing drug discovery and development process.
- Animal tissue ≥ 100 mg
- Cell lines ≥ 1x10^6 cells
- Serum/ Plasma ≥ 200 μL
Thioguanine is a purine derivative with a molecular structure similar to guanine, but with a sulfur atom (S) replacing an oxygen atom at the 5th carbon position, with the chemical formula C₅H₅N₅S. It is an important antimetabolite drug primarily used to treat certain types of cancer, such as acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML). Analyzing the levels of thioguanine and its metabolites can help assess patient responses to cancer treatment. By monitoring these substances, medication dosages can be adjusted to optimize treatment effectiveness and reduce side effects. Thioguanine also possesses immunosuppressive properties and is commonly used to treat autoimmune diseases, such as Crohn's disease and rheumatoid arthritis. Due to its immunosuppressive nature, analyzing its metabolites aids in evaluating its role in the treatment of autoimmune diseases, which is important for adjusting treatment plans and preventing infections.
Figure 1. The Structure of Thioguanine
MtoZ Biolabs offers an exceptional Thioguanine Analysis Service, backed by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and expert metabolomics team. Our service assures a comprehensive analysis of thioguanine, ensuring high sensitivity and accuracy.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Cell lines, serum, plasma, tissues, and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Key Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Thioguanine
4. Raw Data
5. Comprehensive Analysis Report
Our Thioguanine Analysis Service is aimed at facilitating your research and product development by providing accurate and reliable results. Trust MtoZ Biolabs for your thioguanine analysis needs.
How to order?
