Taurocholanic Acid Analysis Service

Taurocholic acid (TCA), also known as cholyltaurine, or acidum cholatauricum, is a deliquescent yellowish crystalline bile acid that plays a key role in the emulsification of fats. TCA occurs naturally as a sodium salt in the bile of mammals and is formed by the conjugation of cholic acid (CA) with taurine. It is critical in the bile acid cycle, aiding in the emulsification and absorption of dietary fats and regulating cholesterol metabolism, while also maintaining liver function. In medical applications, TCA is used as a cholagogue and choleretic, facilitating bile flow and secretion. Abnormal levels of TCA, particularly its excessive accumulation, are closely linked to various hepatobiliary diseases, including cholestasis, cirrhosis, and gallstones. Therefore, accurate analysis of TCA and its metabolites is essential for the diagnosis, research, and treatment of liver and bile duct diseases.

 



Figure 1. Molecular Structure of Taurocholanic Acid

 

MtoZ Biolabs offers Taurocholanic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in TCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of TCA accurately.

 

2. High Specificity

Differentiates TCA from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing TCA and its related metabolites.

 

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

 

Applications

• Hepatobiliary Disease Research
• Cholesterol Metabolism Research
• Lipid Metabolism Research
• Drug Development
• Toxicity Assessment

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Taurocholanic Acid

4. Raw Data

5. Custom Analysis Report

 

Our Taurocholanic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.