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    T-PCS Analysis Service

      T-PCS (Total p-Cresyl Sulfate) is a compound containing a methylphenol group and a sulfate ester group, with a chemical structure consisting of a methyl-substituted benzene ring attached to a sulfate group. This compound is primarily produced through the microbial metabolism of p-cresol in the gut, followed by sulfation in the liver. p-Cresyl sulfate exhibits significant biological activity in the human body, particularly in patients with chronic kidney disease, where it is considered a uremic toxin that may contribute to cardiovascular disease and kidney function deterioration.

       

      The metabolites of p-cresyl sulfate include p-cresol, which have important effects on microbial metabolism and human health. Analyzing the levels of T-PCS and its metabolites in plant and biological samples is crucial for understanding the interactions between gut microbiota and host metabolism and assessing the risk of kidney damage. Additionally, studying the presence of these metabolites in plant samples may help uncover their potential role in plant stress responses.

       

      Services at MtoZ Biolabs

      MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes advanced LC-MS-based metabolomics research platform for the analysis of T-PCS. We guarantee the accuracy of the quantification of T-PCS and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our T-PCS analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.

       

      Analysis Workflow

       

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      Service Advantages

      1. Advance Analysis Platform: MtoZ Biolabs established an advanced T-PCS analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

       

      2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

       

      3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all T-PCS analysis data, delivering clients a detailed and comprehensive data report.

       

      4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.

       

      Applications

      • Discovering new disease biomarkers  
      • Enhancing disease diagnosis  
      • Speeding up the discovery of innovative therapeutics  
      • Uncovering new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples are all applicable for our T-PCS analysis. It is essential that at least three replications of the same condition are selected for each sample type.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      To maintain stability, the samples should be stored at -80°C.

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. In-depth Information Regarding T-PCS

      4. Raw Data

      5. Custom Analysis Report

       

      Through our T-PCS analysis service, we aim to simplify your research and product development processes by providing accurate and reliable results.

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