Succinic Acid Analysis Service

Succinic acid (C₄H₆O₄), a key intermediate in the tricarboxylic acid (TCA) cycle, plays a pivotal role in cellular respiration, where it facilitates the transfer of energy within cells. Structurally, succinic acid is a dicarboxylic acid, featuring two carboxyl groups that contribute to its acidic properties. Succinic acid has a wide range of applications in fields such as medicine, food and beverage, and biotechnology due to its properties as a multi-functional, biodegradable, non-toxic, and naturally occurring compound. It is found in many fermented foods, such as yogurt and sauerkraut, and is also produced during anaerobic fermentation by certain bacteria. Moreover, the measurement and tracking of succinic acid levels can provide critical insights into the cellular function and energy metabolism. Abnormal levels of succinic acid have been associated with several pathological states including mitochondrial disorders, aging, cancer, and metabolic syndromes. Therefore, a precise and detailed analysis of succinic acid is crucial in biomedical research and the development of therapeutic strategies.

 



 

Figure 1. The Structure of Succinic Acid

 

At MtoZ Biolabs, we offer a comprehensive Succinic Acid Analysis Service using LC-MS/MS. We can help you:

• Identify and quantify succinic acid in various biological samples such as plasma, urine, cells, and tissues.
• Understand the role of succinic acid in different biological processes.
• Discover potential biomarkers for disease diagnosis and prognosis.
• Develop novel therapeutic strategies based on succinic acid metabolism.

 

Analysis Workflow

1. Sample Preparation: Samples are carefully prepared to preserve the integrity of succinic acid and other metabolites.

2. Metabolite Extraction: Succinic acid is extracted using optimized extraction methods.

3. Mass Spectrometry Analysis: An advanced Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS) system is used for high-throughput and sensitive detection of succinic acid.

4. Data Analysis: We provide comprehensive data analysis including peak identification, metabolite quantification, and metabolic pathway analysis.

5. Report Generation: A detailed report with all the findings and analysis is provided.

 



 

Service Advantages

• Continuously optimized experimental protocols and analysis software
• Professional experimental design
• Rapid turnaround time
• High accuracy, specificity, and sensitivity

 

Applications

• Drug Discovery
• Biomarker Identification
• Clinical Research
• Nutritional Studies

 

Sample Submission Requirements

 



 

• Samples should be stored at -80℃ and shipped with dry ice.
• Other sample types, please contact us for more details.

 

Deliverables

1. Experimental Procedures

2. Essential Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Succinic Acid

4. Raw Data

5. Custom Analysis Report

 

For more information about our Succinic Acid Analysis Service, please contact us at MtoZ Biolabs. Our team of experts is ready to assist you with your research needs.