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    Ritalinic Acid Analysis Service

      Ritalinic acid is a monocarboxylic acid that is phenylacetic acid substituted by a piperidin-2-yl group at position 2. It is a metabolite of the drug methylphenidate. It has a molecular formula of C₁₃H₁₇NO₂ and a molecular weight of 2219.28 g/mol. As the primary active metabolite of methylphenidate, ritalinic acid is directly involved in the drug's mechanism by contributing to its pharmacological effects. The accurate quantification of ritalinic acid and its metabolites in biological fluids, such as serum and urine, is crucial for evaluating the therapeutic efficacy of methylphenidate and optimizing treatment strategies for disorders like ADHD (Attention Deficit Hyperactivity Disorder) and narcolepsy. By quantitatively analyzing ritalinic acid, healthcare professionals can assess a patient's response to the medication, ensuring that therapeutic levels are maintained while minimizing potential side effects.

       

      Moreover, analyzing the levels of ritalinic acid and its metabolites provides insights into the absorption, metabolism, and excretion processes of methylphenidate in patients. This information is vital for determining the drug's effectiveness and identifying any potential toxic reactions, particularly in patients who do not respond adequately or experience adverse effects. Additionally, such analysis helps identify patients with abnormal metabolic profiles, such as those with impaired liver function or metabolic complications arising from drug interactions.

       

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      Figure 1. The Structure of Ritalinic Acid

       

      MtoZ Biolabs provides a top-tier Ritalinic Acid Analysis Service utilizing our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and an experienced metabolomics team. Our service delivers a thorough ritalinic acid analysis ensuring high sensitivity and accuracy.

       

      Analysis Workflow 

       

      1834065407611883520-WorkflowofRitalinicAcidAnalysisService.PNG

       

      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms.
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      1. Novel biomarker discovery

       

      2. Disease diagnosis enhancement

       

      3. Accelerating the development of innovative therapeutic interventions

       

      4. Unveiling new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. At least 3 samples under the same conditions are required for each type. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Preserve at -80°C to maintain stability. 

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Appropriate Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Ritalinic Acid

      4. Raw Data

      5. Personalized Analysis Report

       

      Through our Ritalinic Acid Analysis Service, we aim to support your research and product development by providing precise and trustworthy results. If you have any questions or would like to learn more about our analysis services, please feel free to contact us. We look forward to collaborating with you to advance scientific research and clinical applications.

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