Ricin Analysis Service

    Ricin is a highly toxic, naturally occurring protein derived from the castor oil plant, Ricinus communis. It is a ribosome-inactivating protein that inhibits protein synthesis leading to cell death. Due to its high toxicity, ricin is often used as a biological weapon. Accurate identification and quantitation of ricin is crucial for forensic, environmental, and food safety applications.

     

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    Figure 1. The Structure of Ricin

     

    Technical Principles

    At MtoZ Biolabs, we use a combination of high-resolution liquid chromatography-tandem mass spectrometry (LC-MS/MS) and metabolomics techniques for ricin analysis. LC-MS/MS is a powerful analytical tool that separates compounds based on their mass-to-charge ratio, providing highly accurate and sensitive detection of ricin.

     

    By coupling LC-MS/MS with metabolomics, we can profile entire metabolic networks affected by ricin, gaining a holistic view of its impact on biological systems. This not only allows us to detect and quantify ricin, but also to understand the downstream effects of its toxicity.

     

    Analysis Workflow

     

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    Service Advantages

    • Advanced LC-MS equipment with high sensitivity and accuracy
    • Comprehensive data analysis supported by a team of experienced analysts
    • Strict quality control to ensure reliable results
    • Personalized service to meet various research needs

     

    Applications

    Our Ricin Analysis Service can be used for a wide range of applications including:

    • Forensic investigations
    • Environmental monitoring
    • Food safety testing
    • Biodefense research

     

    Sample Submission Requirements

    • Type of samples: Animal tissue, plasma, serum, plant materials, cell, etc.
    • Quantity: At least 200 μl liquid, 1 x 10⁷ cells, or 200 mg tissue.
    • Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.
    • Avoid repeated cycles of freezing and thawing
    • More than 6 biological replicates should be prepared.

    For more details, please feel free to get in touch with our customer service team.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Ricin Analysis

    4. Raw Data

    5. Custom Analysis Report

     

    For further information, please contact our customer service team. We are looking forward to assisting you with your research needs.

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