Retinoic Acid Analysis Service
- Discovery of new disease biomarkers
- Enhancing disease diagnosis
- Accelerating the discovery of novel therapeutics
- Unraveling new insights into disease mechanisms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Retinoic acid (RA) is a metabolite of vitamin A and a derivative of retinaldehyde, serving as an important endogenous bioactive molecule. Its chemical formula is C20H28O2, and it has a molecular weight of 300.44 g/mol. RA functions as a critical signaling molecule involved in various biological processes, including embryonic development, cell proliferation and differentiation, tissue regeneration, and immune responses. By analyzing the levels of RA and its metabolites, it is possible to study the dynamic changes of RA during different developmental stages, thereby understanding its role in various phases of development. Additionally, RA plays a significant role in the regulation of immune cell functions, including T cell differentiation, B cell activation, and inflammatory responses. Variations in RA levels are closely associated with autoimmune and inflammation-related diseases, such as inflammatory bowel disease and psoriasis. Therefore, analyzing the levels of RA and its metabolites can provide insights into its mechanisms in immune regulation.
Figure 1. The Structure of Retinoic Acid
MtoZ Biolabs offers a state-of-the-art Retinoic Acid Analysis Service, leveraging our cutting-edge liquid chromatography-mass spectrometry (LC-MS) platform and seasoned metabolomics team. Our service ensures a comprehensive retinoic acid analysis, revealing the functional mechanisms of retinoic acid in both normal and abnormal states and providing new targets and strategies for the diagnosis, treatment, and prognosis of related diseases.
Analysis Workflow
Service Advantages
1. High Sensitivity and Accuracy
MtoZ Biolabs' liquid chromatography-mass spectrometry (LC-MS) analysis platform can detect extremely low concentrations of RA and its metabolites, which is particularly important for studying their minute changes in cells, tissues, and bodily fluids.
2. High Specificity
By optimizing chromatographic separation conditions and mass spectrometry detection parameters, RA and its various metabolites can be effectively distinguished in complex biological samples, minimizing interference from other endogenous or exogenous substances and improving detection specificity.
3. Customized Analysis
Tailored analytical solutions can be designed according to research needs, providing personalized solutions for different biological samples and target molecules.
4. Real-Time Dynamic Monitoring
The levels of RA and its metabolites can be continuously monitored under different conditions and at various time points, making it suitable for studying their dynamic changes in biological processes such as embryonic development, cell differentiation, immune response, and disease states.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. It is required to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Samples should be stored at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Retinoic Acid
4. Raw Data
5. Custom Analysis Report
Through our retinoic acid analysis service, we aim to assist your research and product development endeavors by providing precise and reliable results. If you are interested in our related services, please feel free to contact us.
How to order?
