Respiratory Diseases Metabolomics Service

    Respiratory diseases (including chronic obstructive pulmonary disease, asthma, pneumonia, lung cancer, etc.) are among the most common diseases worldwide, with both morbidity and mortality rates continuing to rise. At present, the pathogenesis of respiratory diseases is not fully understood, posing a significant challenge to early prevention and personalized treatment of diseases. Therefore, a deep understanding of the pathogenesis of respiratory diseases, finding effective biomarkers, and developing targeted drugs are important topics in current respiratory disease research.

     

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    Barberis, E. et al. Metabolites. 2021.

    Figure1. Identification of Potential Biomarkers Associated With SARS-CoV-2 Infection Using Non-targeted Metabolomics

     

    Services at MtoZ Biolabs

    MtoZ Biolabs offers metabolomics solutions for respiratory diseases, helping to identify accurate biological diagnostic markers, explore the pathogenesis, and develop targeted drugs. Our services include:

     

    1. Metabolomics analysis of respiratory diseases

    ● Metabolite level measurement

    ● Biomarker discovery for respiratory diseases

    ● Mechanism research of new drugs

     

    2. Metabolomics analysis of airway inflammation and asthma

    ● Measurement of inflammation-related metabolite levels

    ● Asthma-related biomarker discovery

    ● Mechanism research of inflammation and asthma drugs

     

    Experimental Instruments

    We use multiple analysis platforms, including GC-MS, LC-MS, and UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive method for deeply understanding the mechanism of the disease.

     

    1. Chromatography

    • GC (Q Exactive) (- mode MS)
    • HPLC: HILIC (+/- mode MS)
    • HPLC: RP C18 (+/- mode MS)
    • IC (- mode MS)

     

    2. Mass Spectrometry

    • Q Exactive MS
    • Orbitrap Tribrid mass spectrometry

     

    MtoZ Biolabs is a mature partner in pharmaceutical research with rich experience in metabolomics analysis. We provide metabolomics solutions for respiratory diseases, accelerating the exploration of new scientific horizons. If you want to learn more, please contact us. We look forward to collaborating with you.

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