Resources

Proteomics Databases



Metabolomics Databases

• • Monoclonal Antibody Characterization Techniques

  Monoclonal antibody characterization techniques are essential for the detailed analysis and description of the properties of monoclonal antibodies. These antibodies, produced from a single B cell clone, exhibit high specificity and consistency, making them invaluable in diagnostics, therapeutics, and scientific research. The primary goal of characterization techniques is to thoroughly assess and control the structural, functional, and stability attributes of antibodies using diverse analytical methods......

• • Drug Target Identification

  Drug target identification is the process of using various techniques to identify and confirm specific biomolecules in organisms that interact with drugs to regulate disease-related biological processes. With the increasing complexity of diseases, traditional drug development methods face significant challenges. This approach offers a more precise strategy to target specific disease mechanisms while minimizing effects on other physiological functions.   Drug target identification has applications acro......

• • Characterization of Protease

  Characterization of protease involves a detailed analysis of their structure, function, and roles within biological systems. As enzymes that catalyze the hydrolysis of proteins, proteases are ubiquitous in living organisms and are integral to processes such as digestion, cell proliferation, signal transduction, and immune response. Altered expression or activity of proteases is often linked to diseases like cancer, neurodegenerative disorders, and cardiovascular conditions. Thus, characterization of p......

• • Single-Molecule Proteomics

  Single-molecule proteomics (SMP) is an advanced proteomics technology designed to detect, quantify, and analyze proteins at the single-molecule level. Unlike traditional proteomics, which relies on large sample sizes, single-molecule proteomics enables the study of protein diversity, heterogeneity, and post-translational modifications (PTMs) using minimal sample amounts or even single cells. This groundbreaking approach provides new insights into cellular functions, disease mechanisms, and personalize......

• • Isoform Sequencing

  Isoform sequencing is a method used to characterize the sequences of isoforms, which are distinct transcripts or protein forms originating from the same gene. These isoforms are generated through mechanisms such as alternative splicing, alternative promoter selection, and RNA editing. This approach enables a deeper understanding of the complexity and diversity of gene expression, which is crucial for elucidating cellular functions and disease mechanisms.   Isoform sequencing examines genes or genomic ......

• • Cryogenic Electron Microscope

  Cryogenic Electron Microscope is an advanced imaging technique that leverages electron beams to visualize biological samples at ultra-low temperatures. By preserving samples in their near-native state through rapid vitrification, Cryogenic Electron Microscope offers unprecedented resolution for studying the intricate structures of biomolecules. The workflow of Cryogenic Electron Microscope involves four key steps: sample preparation, vitrification, data acquisition, and image reconstruction. Samples a......

• • Cryo Microscopy

  Cryo microscopy, also known as cryo-electron microscopy (cryo-EM), is a transformative technology for investigating the structures of biological macromolecules. By rapidly freezing samples to preserve their native states, cryo-EM captures high-resolution images without compromising structural integrity. This capability has established cryo-EM as an indispensable tool in structural biology, enabling researchers to study complex biological systems such as proteins, viruses, and cellular membranes un......

• • Single-Nuclear RNA Sequencing

  Single-nuclear RNA sequencing(snRNA-Seq) is an advanced high-throughput technology designed to analyze RNA expression at the level of individual cell nuclei. This approach has become increasingly valuable in biomedical research due to its ability to reveal cellular heterogeneity, track cell differentiation trajectories, and decipher tissue complexity. Unlike traditional methods that require whole-cell dissociation, single-nuclear RNA sequencing directly isolates RNA from intact nuclei, preserving the ......

• • Single-Cell Long-Read Sequencing

  Single-Cell Long-Read Sequencing is an advanced technology that enables the comprehensive characterization of genomic and transcriptomic information at the single-cell level. By integrating the strengths of single-cell resolution and long-read sequencing, this approach addresses limitations associated with traditional short-read sequencing methods, such as difficulties in resolving complex genomic rearrangements, identifying full-length isoforms, and analyzing gene families. Long-read sequencing gener......

• • Molecule Discovery

  Molecule discovery refers to the identification and characterization of biomolecules and their biological functions. At its core, this technology seeks to pinpoint proteins, nucleic acids, metabolites, and other critical molecules involved in specific biological processes. Beyond advancing fundamental science, molecule discovery has far-reaching applications in clinical medicine, drug development, and agricultural innovation. For instance, researchers use this approach to identify disease biomarkers, ......