Resources

Proteomics Databases



Metabolomics Databases

• • How to Detect Collagen Protein

  Although collagen accounts for about 30% of the total protein in the human body, it can be difficult to purify and analyze due to the extensive network of collagen molecules formed by different types of cross-linking, which makes collagen insoluble and difficult to extract.

• • Detecting HCP Using WB Method

  HCP (Host Cell Proteins) are proteins produced by host cells that are used in the production of biopharmaceuticals and may contaminate the final therapeutic product. The detection and quantification of HCP is an important step in the development and production process of biopharmaceuticals, as HCP can have adverse effects on the safety, purity, and potency of the drug.

• • Infrared Spectroscopy Analysis Method

  Infrared spectroscopy is a commonly used method for analyzing the structure of substances. When molecules absorb infrared radiation at specific frequencies, their vibrational states change, resulting in an infrared spectrum. Through infrared spectroscopy, we can obtain information about the functional groups, structures, and other related properties of a substance.

• • Protein Phosphorylation Detection by GST in Vitro

  Extracellular GST (Glutathione S-Transferase) protein phosphorylation detection is an experimental method used to study the phosphorylation status of proteins. This method combines the purification technique of GST fusion proteins with phosphorylation status detection techniques to analyze the phosphorylation level of specific proteins or protein domains. Using this method, researchers can study the phosphorylation status of proteins under specific conditions of signal pathway activation or inhibition.

• • Class Generalization Level Inspection

  SUMO (Small Ubiquitin-like Modifier)ylation is an important protein post-translational modification process that involves the covalent attachment of SUMO proteins to specific lysine residues on target proteins. This modification is crucial for regulating protein localization, stability, activity, and involvement in processes such as cell cycle control, DNA damage repair, and signal transduction.

• • Ubiquitin Labeling Free Mass Spectrometry Analysis

  Ubiquitination is a crucial post-translational modification process, involving the attachment of the small ubiquitin protein to target proteins via covalent bonds. This modification can regulate the stability, activity, localization, and other functions of the target protein. Mass spectrometry analysis of ubiquitination can identify the proteins that are ubiquitinated, as well as the exact sites of ubiquitination.

• • Identification of Lactylation Modification Sites in Proteins

  Lactylation of proteins is a novel post-translational modification (PTM) that is widely present in fungi and mammalian cells, such as humans and mice. It directly stimulates gene transcription and significantly affects downstream gene expression and DNA replication. Understanding the role and regulatory mechanisms of lactylation in highly glycolytic and lactic acid-dependent physiological and pathological processes is crucial.

• • Histone Acetylation Modification Mass Spectrometry Analysis

  Histone acetylation is an important post-translational modification (PTM) of proteins that plays a critical role in gene expression regulation, chromatin remodeling, and other cellular functions. Mass spectrometry has become an important tool for identifying and quantifying protein acetylation modifications.

• • Analysis of Antibody Constant Region Sequence

  The constant region of an antibody, also known as the Constant Region, is a part of the antibody molecule that is responsible for stabilizing its structure in order to carry out its specific immune functions. The constant region of an antibody is typically located at the bottom of the molecule, near the antibody's tail, and corresponds to the variable region of the antibody, which is responsible for recognizing and binding to antigens.

• • How to Detect Abnormal Glycoproteins

  Glycoproteins, also known as glycoproteins, are molecules that have one or more sugar chains attached to their protein structure. The structure and composition of these sugar chains play important roles in many biological processes, including cell recognition, signal transmission, and immune response.