Resources

Proteomics Databases



Metabolomics Databases

• • Circular Dichroism: Analyzing Chiral Molecules and Biomolecule Structures

  Circular dichroism spectroscopy is an experimental method used to analyze molecular structure and chirality properties, commonly applied in the fields of chemistry, biochemistry, and biophysics. This technique utilizes the optical activity of substances when interacting with circularly polarized light to obtain information.

• • Host Protein Residue Detection: Key to Biopharmaceuticals

  Host protein residual detection refers to the detection of proteins derived from the production cell line (i.e., host) that may remain in the final product during the biopharmaceutical production process. This type of detection is crucial because these host cell proteins (HCPs) may affect the safety, efficacy, and quality of the drug product.

• • HCP Residual Detection: Ensuring Biopharmaceutical Safety and Quality

  HCP (Host Cell Proteins) residual detection is a critical quality control step in the field of biopharmaceuticals, aimed at ensuring that the levels of host cell proteins in the final drug product remain at acceptable low levels in any cell-based production system used to produce therapeutic proteins.

• • Nasopharyngeal Carcinoma Tissue MRM/PRM Quantitative Proteomic Analysis

  Nasopharyngeal carcinoma is a malignant tumor originating from the epithelium of the nasopharyngeal mucosa. Its incidence and mortality rates vary significantly geographically, particularly more common in Southeast Asia. Early diagnosis and treatment of nasopharyngeal carcinoma are crucial, however, due to the specific anatomical location of the nasopharynx, early symptoms are not obvious, often leading to late-stage detection of the disease.

• • DLS Particle Size Analyzer: Overview and Testing Steps

  Dynamic Light Scattering (DLS), also known as photon correlation spectroscopy or quasi-elastic light scattering, is a technique used to measure the size distribution of particles (such as proteins, polymers, nanoparticles, etc.) in a solution. In DLS experiments, a liquid sample is illuminated by a laser beam, and the particles in the solution cause the laser to scatter.

• • Protein Thermal Stability: Influencing Factors and Applications

  The thermal stability of proteins refers to their ability to maintain their three-dimensional structure at high temperatures, which is crucial for their biological functions. Protein denaturation, or loss of structure, usually leads to loss of function.

• • Absolute Quantification Analysis of Vitreous Humor Tissue Proteins

  The vitreous humor is a gel-like transparent substance located at the back of the eye, which maintains the shape of the eye and plays a crucial role in preserving the health of the retina. The protein component in the vitreous humor can reflect the health status of the eye, including retinal disease, glaucoma, and ocular complications of systemic diseases like diabetes.

• • Human Cell Peptide Proteomic Analysis

  In the vast field of biomedical research, the analysis of human cell peptidomics occupies a central position. This analysis is crucial for understanding cell function, disease mechanisms, and drug action. Advanced peptidomics analysis services provided by MtoZ Biolabs aim to reveal the complex peptide dynamics and their functions within human cells.

• • Edman: a Classical Biochemical Way to Reveal the N-Terminal Amin

  Edman degradation, also known as Edman sequencing, is a biochemical method used to determine the N-terminal amino acid sequence of a protein. This method was first proposed by American biochemist Pehr Edman in 1950 and has been continuously improved and applied in the following decades. The Edman method is typically used to analyze the amino acid sequence of smaller proteins or peptide segments and involves the following steps.

• • Analysis of Post-Translational Modifications of Plant Leaf Histones

  Protein translation and post-translational modification analysis in plant leaf blades is a key research field that delves into the genetic regulation and protein function in plants. Histones are core proteins that bind to DNA, forming chromatin structures and playing essential roles in gene expression.