Resources

Proteomics Databases



Metabolomics Databases

• • Mechanism of Protein Molecular Weight Determination by MS

  Protein molecular weight determination is a cornerstone in the field of proteomics, aiding in the identification and characterization of proteins. Mass spectrometry (MS) has emerged as a pivotal technique for this purpose, offering high sensitivity, accuracy, and speed.

• • Mechanism of MS-Based Protein Interaction Identification

  Proteins are crucial biomolecules in cells, performing complex biological functions through various interactions. Understanding protein-protein interactions is essential for revealing the mechanisms of biological processes. Recently, mass spectrometry-based protein interaction identification (MSPII) has gained attention due to its high sensitivity, throughput, and precision.

• • Application of MS-Based Protein Interaction Identification

  Mass spectrometry (MS) is a highly sensitive analytical technique widely employed in proteomics. The identification of protein-protein interactions (PPIs) using mass spectrometry holds a pivotal role in biological research. This article provides a detailed overview of the applications of mass spectrometry in the identification of protein-protein interactions.

• • Workflow of MS-Based Protein Interaction Identification

  Mass spectrometry (MS) has become a crucial tool in modern proteomics, particularly for identifying protein-protein interactions. MS technology allows for accurate and rapid identification and quantification of dynamic changes in protein interactions. This article provides a detailed overview of the workflow for identifying protein-protein interactions using mass spectrometry, aiding researchers in understanding and applying this technology effectively.

• • Advantages and Disadvantages of MS-Based Protein Interaction Identification

  Understanding protein-protein interactions is crucial for uncovering complex physiological and pathological processes in organisms. In recent years, mass spectrometry (MS)-based techniques have gradually become the preferred tool for researchers studying these interactions. This article explores the advantages and disadvantages of mass spectrometry-based identification of protein-protein interactions.

• • Mechanism of Unknown Protein Identification

  With the rapid advancement of genomics and proteomics technologies, many previously unknown proteins have been discovered. However, the functions and mechanisms of these proteins remain largely unexplored. Identifying the mechanisms of unknown proteins is crucial for understanding biological processes, discovering new drug targets, and developing new therapeutic approaches. This article explores the current mechanisms and methods used to identify unknown proteins in detail.

• • Principle of MS-Based Protein Interaction Identification

  Proteins are essential in numerous physiological processes within cells. Understanding protein functions necessitates studying their interactions. Traditional methods such as yeast two-hybrid and co-immunoprecipitation, though effective, have limitations. Mass spectrometry (MS) has emerged as a sensitive and efficient tool for studying protein-protein interactions in recent years.

• • Application of Unknown Protein Identification

  The identification of unknown proteins is a pivotal aspect of contemporary biological research. With the advent of genome sequencing technology, we have access to an immense amount of protein sequence data. However, the functions of numerous proteins remain elusive. Identifying these unknown proteins using advanced methodologies not only propels basic scientific research forward but also significantly impacts various application fields.

• • Workflow of Unknown Protein Identification

  Proteins are vital components of living organisms, responsible for executing many critical physiological functions. Despite the extensive identification and functional analysis of many proteins, there remain numerous proteins whose functions are not fully understood. Identifying unknown proteins is a complex and precise task involving multiple steps and techniques.

• • Mechanism of Protein Identification by Tandem MS

  Proteins are the fundamental units of life activities, and studying their structure and function is crucial for understanding biological processes. Mass spectrometry, especially tandem mass spectrometry (MS/MS), has become the primary tool for protein analysis. Using protein tandem mass spectrometry for identification, we can gain deep insights into protein composition, structure, and function, thereby uncovering complex biological mechanisms.