Resources

Proteomics Databases



Metabolomics Databases

• • Vitreous Humor Tissue Protein 2D Electrophoresis Analysis

  The vitreous humor tissue is a crucial tissue in the eye and plays a vital role in the normal functioning of the visual system. It contains various proteins that are closely related to eye diseases, aging, and other physiological processes. Therefore, the identification and quantification analysis of its proteins are of great significance.

• • Comparison of Proteomics Analysis

  Comparative proteomics is a branch of proteomics that involves comparing protein expression in different biological samples, such as cells in healthy and diseased states or cells from different species. This comparison can reveal which proteins have changed under specific conditions, helping scientists understand disease mechanisms, identify biomarkers, and even discover new therapeutic targets.

• • Drug Antibody Testing

  Drug antibody testing is a laboratory testing method specifically designed to evaluate the immune response of the human body to certain drugs. This test is commonly used to monitor a patient's immune response to biological agents or other drugs, especially in the treatment of chronic diseases such as autoimmune diseases, certain cancers, and inflammatory diseases. The principle of drug antibody testing is based on the recognition and response of the immune system to drug molecules.

• • TMT vs Label Free

  TMT is a chemical labeling method used for quantitative proteomics. Peptides from different samples are chemically labeled with different isotopic labels. These labels are designed to have the same mass, but when broken down in a mass spectrometer they will release different reporter ions. The relative abundance of peptides in different samples can be determined by comparing the intensities of these reporter ions.

• • Targeted Proteomics

  Targeted proteomics is a mass spectrometry method that focuses on studying a specific set of proteins or peptides, in contrast to traditional global proteomics analysis. Targeted proteomics typically uses selected reaction monitoring (SRM) or multiple reaction monitoring (MRM) techniques to specifically detect and quantify specific peptide segments.

• • Protein Amino Acid Composition Analysis

  Protein amino acid composition analysis is to understand the basic composition of proteins by determining the types of amino acids they contain and their relative molar ratios. This analysis method is commonly used to identify, quantify and study the chemical properties and structure of proteins and peptides. Below are some techniques commonly used for protein amino acid composition analysis:

• • TMT Quantitative Mass Spectrometry

  TMT (Tandem Mass Tag) is a widely used technique in quantitative proteomics. TMT is a chemical labeling method used for quantitative proteomics. Peptides from different samples are labeled with different isotopic tags. These tags have the same mass in the mass spectrometer, but when they are fragmented in the mass spectrometer, they release different reporter ions. By comparing the intensities of these reporter ions, the relative abundance of peptides in different samples can be determined.

• • Fundamentals of Infrared Spectroscopy and Spectrum Analysis

  Infrared spectroscopy (IR) is an experimental technique widely used in the fields of chemistry, biology, and materials science. Its basic principle is that chemical bonds in molecules absorb infrared radiation at specific frequencies, resulting in vibrational motion of the bonds. Infrared spectra display the specific frequencies at which a material absorbs infrared radiation.

• • Number of Replicate Samples in Epigenomics Experiments

  In epigenomic experiments, parallel samples are used to ensure the reliability and reproducibility of experimental results. The choice of the number of parallel samples depends on various factors, including experimental design, expected variability, and data analysis methods.

• • Analysis of mRNA 5' Capping Rate in Brain Tissue

  The 5' cap of mRNA in brain tissue is a crucial biological process that is essential for regulating gene expression and cellular function. The 5' cap structure of mRNA not only protects mRNA from degradation by exogenous nucleases, but also facilitates its nuclear export, localization, and translation. This regulation is particularly important in the nervous system as it affects neuronal signaling, neuronal cell survival, and overall brain function.