Resources

Proteomics Databases



Metabolomics Databases

• • Workflow of Glycoprotein Detection Using LC-MS

  Glycoproteins play a critical role in various biological processes, including cell recognition, signal transduction, and immune responses, primarily due to their glycosylation modifications. Studying these glycosylation patterns can help elucidate molecular mechanisms behind diseases such as cancer and immune disorders. LC-MS (Liquid Chromatography-Mass Spectrometry) is a widely used technique for detecting and characterizing glycoproteins' glycosylation modifications.

• • Advantages and Disadvantages of Glycoprotein Analysis Methods

  Glycoproteins are a class of proteins that are widely present in living organisms and play essential roles in biological processes such as protein regulation, cell communication, and immune responses through glycosylation. Changes in glycosylation are often associated with various diseases, including cancer and metabolic disorders.

• • Principle of Glycoprotein Analysis Based on Mass Spectrometry

  Glycoproteins are biomolecules where proteins are covalently bonded with carbohydrate chains, playing vital roles in cellular recognition, signal transduction, immune regulation, and other biological processes. Glycosylation, one of the most complex post-translational modifications, significantly affects the structure, stability, and function of proteins. Hence, accurate analysis of glycoproteins is critical for understanding biological processes and developing disease biomarkers.

• • Mechanism of N-glycan Analysis Using HILIC-UHPLC

  N-glycosylation is a crucial post-translational modification of proteins, widely present in eukaryotic cells. It plays an important role in various biological processes, such as protein folding, stability, cell recognition, and signal transduction. Therefore, accurate analysis of protein N-glycosylation is essential for understanding many biological phenomena and disease mechanisms. N-glycan analysis involves the separation, identification, and quantification of glycan structures.

• • Protein Amino Acid Composition Analysis: Methodology and Practice

  Protein is one of the most important molecules in living organisms and plays a critical role in the structure and function of cells. Understanding the amino acid composition of proteins is crucial for understanding their function and structure.

• • Practical Guide to Monosaccharide Composition Analysis: Enhancing Sample Analysis Efficiency

  Monosaccharides are the basic units that make up polysaccharides and are of great importance in the field of biopharmaceutical research and development. Monosaccharide composition analysis is a key technique that can help scientists understand the structure and characteristics of polysaccharides. However, traditional methods for monosaccharide composition analysis suffer from low efficiency.

• • IR Spectrum Analysis Steps: Decoding Information from Spectra to Compounds

  Infrared spectroscopy is a commonly used analytical tool that helps scientists determine the structure and functionality of compounds. By analyzing an infrared spectrum, we can understand the presence and types of functional groups and chemical bonds in a compound.

• • IR Spectral Analysis Principles: Revealing Information from Spectra to Structure

  Infrared spectroscopy is a commonly used analysis technique that provides information about the structure and chemical composition of a sample by measuring its absorption and scattering of infrared light.

• • Peptide Secondary Structure Circular Dichroism: Deep Insights into the Mysteries of Protein Folding

  Protein is one of the most crucial molecules in living organisms, playing a key role in the structure and function of cells. The function of proteins is often closely related to their folding state, which is influenced by the secondary structure of peptides.

• • Introduction to Host Cell Protein Isoelectric Point Analysis

  Host Cell Protein (HCP) refers to impurity proteins that are unrelated to the target protein and expressed by the host cells during the biopharmaceutical manufacturing process. These HCPs can potentially affect the quality, safety, and efficacy of the drug, making the analysis and control of HCPs crucial in the development and production of biologics.