Resources

Proteomics Databases



Metabolomics Databases

• • Proteomics Unveiling the Cell Proteome

  The Importance of Proteomics Proteins, as the building blocks of life, are the main executors of cellular activities. The variations in the types, quantities, structures, and functions of proteins directly impact the life processes of organisms. Proteomics, the scientific study of proteins, investigates the expression, modifications, interactions, and functions of proteins in a comprehensive and systematic manner.

• • Comprehensive Analysis of Proteomics Research

  Proteomics, as an important branch of biological science, is a discipline that comprehensively studies the structure and function of all proteins in an organism. It focuses on proteins as the research object and uses high-throughput techniques to reveal protein expression, modification, interactions, and their functions in organisms.

• • Mass Spectrometry TMT Technology

  TMT mass spectrometry (Tandem Mass Tag) technology is a qualitative and quantitative peptide research technique based on mass spectrometry. TMT technology uses chemical labeling reagents to label peptides in whole protein extracts, enabling their separation in mass spectrometers and even distinguishing differences in single amino acid residues. This is a powerful tool for accurately identifying protein expression differences.

• • Insights into Amino Acid Content Determination Methods

  Amino Acids and the Origin of Life Amino acids, as the building blocks of life, are the fundamental elements that make up proteins. The types and proportions of amino acids determine the structure and function of proteins. Therefore, accurate determination of amino acid content is crucial for understanding protein conformation in living organisms.

• • The Differences Between Histone Ubiquitination and Phosphoproteomics

  Protein modification plays a crucial role in understanding cellular signaling and disease mechanisms in the field of biopharmaceuticals. Ubiquitination and phosphorylation are two common protein modification methods that play indispensable roles in cellular processes.

• • Studying Specific Acetylation Sites on Histones Using WB

  Histone acetylation is a common protein modification that changes the function and structure of proteins by adding acetyl groups to specific sites on the histone protein chain. Histone acetylation plays an important regulatory role in cells and is involved in regulating processes such as gene expression, cell cycle, and cell differentiation.

• • Main Types of Modifications on Histones

  Histone is one of the most important proteins in the cell nucleus, playing a crucial role in maintaining genome structure and function. However, histones are not static, as they can be regulated through a series of modifications that affect gene expression and chromatin state. This article will introduce the main types of histone modifications and explore the applications and prospects of glycan identification in research.

• • Glycosylation Identification of Recombinant Proteins

  Glycosylation is an important protein modification method that plays a key role in cellular signal transduction, protein stability, and functional regulation. By identifying glycosylation of recombinant proteins, researchers can explore new targets and further analyze the association between these targets and cellular function.

• • The Distribution and Functional Analysis of Acetylation Modification on Histones

  Acetylation modification is a common protein modification method, which refers to the addition of an acetyl group (CH3CO-) to the protein. This modification mainly occurs on histones, which are the major components of chromatin and play an important role in gene expression regulation.

• • What Common Techniques and Methods Are Used in Glycomics MS?

  Glycomics is the discipline that studies the composition, structure, and function of sugar molecules in living organisms. Sugar molecules play important roles in biological processes such as cell signaling, protein modification, and immune response. Glycomics research is significant for understanding disease mechanisms, drug development, and biotechnology. Mass spectrometry is one of the commonly used techniques in glycomics analysis.