Resources

Proteomics Databases



Metabolomics Databases

• • Quantification of Free Radicals in Antibody Drugs

  Antibody drugs are a class of protein drugs that target specific targets (cell surface proteins) within the body. They are essentially antibodies with a single determinate specificity produced by a single B lymphocyte clone or its derivative. Antibody drugs are mainly produced through artificial synthesis or biotechnology, and these drugs can specifically recognize and bind to specific targets (usually proteins) within the body to achieve therapeutic effects.

• • Recombinant Protein Drug and Receptor Affinity Detection

  Recombinant protein drugs are protein-based therapeutic drugs produced using DNA recombinant technology or other biotechnological methods. They include cytokines, peptide hormones, recombinant enzymes, monoclonal antibodies, fusion proteins, and so on. Compared to traditional small molecule synthetic drugs, recombinant protein drugs have advantages such as high specificity, low toxicity, and significant therapeutic effects.

• • Regulatory Mechanisms of Protein Glycosylation Modifications

  Glycosylation modification of proteins plays a critical role in cellular functions and signal transduction, serving as an important biochemical modification. Glycosylation modification can affect the stability, activity, localization, and interactions of proteins, thereby regulating various biological processes.

• • Glycosylation Analysis Reveals Diversity and Function of Protein Modifications

  Protein glycosylation modification, as an important biochemical process, plays a crucial role in cellular function and signal transduction. Glycosylation modification can not only alter the biological activity and stability of proteins but also participate in regulating important biological processes such as protein-protein interactions, recognition, and mediation of cell-cell interactions.

• • Glycoprotein Identification Unveils Structure-Function Relationship of Glycosylated Proteins

  Glycoproteins are a class of proteins that undergo glycosylation modification, playing important structural and functional roles in organisms. Studying the relationship between the structure and function of glycoproteins has significant implications for understanding cellular signal transduction, the immune system, and disease development.

• • Proteomics Analysis Revealing Protein Composition and Function in Biological Systems

  Proteins are one of the most important molecules in biological systems, playing various crucial roles within cells. Understanding the composition and functions of proteins is essential for studying biological processes, developing drugs, and diagnosing diseases. However, the complexity and diversity of proteins make their study challenging. In order to address these issues, proteomic analysis has emerged.

• • Detection of Membrane Proteins with High-Resolution Mass Spectrometry

  Membrane proteins are vital components of the cellular membrane, playing essential roles in substance transport, signal transduction, and intercellular communication. Given their biological significance, the study of membrane proteins has become a focus in life sciences. However, due to their low solubility and complex structural features, the isolation and analysis of membrane proteins present substantial challenges.

• • Functional Analysis of Membrane Proteins Using Orbitrap LC-MS

  Membrane proteins perform various critical biological functions, such as signal transduction, substance transport, and intercellular communication. However, due to their hydrophobic nature and complex structures, functional analysis of membrane proteins has long been a challenge in biological research.

• • Proteomics Workflow in Paraffin-Embedded Tissue Samples

  Formalin-Fixed Paraffin-Embedded (FFPE) tissue samples are frequently used in clinical pathology for long-term preservation of biological specimens. The formalin fixation process, while preserving tissue structure, induces protein cross-linking, presenting challenges for downstream proteomics analysis. However, with carefully optimized workflows, researchers can successfully perform proteomic studies on FFPE tissues.

• • Proteomics Analysis of Exosome Samples Based on LC-MS/MS

  Exosomes are nanoscale vesicles secreted by cells, containing proteins, lipids, nucleic acids, and other biological molecules. They play a crucial role in intercellular communication, immune regulation, tumor metastasis, and various physiological and pathological processes, making them a hotspot in biomedical research.