Resources

Proteomics Databases



Metabolomics Databases

• • Mass Cytometry Markers Revealing Cellular Heterogeneity

  Mass cytometry, as an important tool in the field of biopharmaceutical research, has revealed the secrets of cells by accurately measuring protein expression.

• • Mass Cytometry Sample Preparation and Analysis Steps

  In mass spectrometry flow analysis, sample preparation is the first step of the journey and an important part that affects the subsequent analysis. The following steps are essential in the experimental process.

• • How to Optimize Analysis Results of Mass Cytometry Single-Cell Protein Detection?

  Entering the smallest unit of the human body - individual cells, exploring the mysteries of their proteins, mass spectrometry flow cytometry has opened a new window for us to explore the world. This technology can detect thousands of proteins from a single cell, allowing us to decipher the life code of each cell.

• • Disulfide Proteomics Detection and Mass Spectrometry Techniques

  Disulfide bonds play a crucial role in biological systems, as they provide a stable three-dimensional structure to proteins and regulate their functions by connecting two cysteine residues. For example, insulin, a commonly active hormone in the human body, contains disulfide bonds.

• • The Significance of Phosphorylation Site Identification by Mass Spectrometry

  Protein phosphorylation is an extremely important biological process that is directly associated with many life phenomena. Mass spectrometry technology for identifying phosphorylation sites on proteins is gradually becoming a new direction in disease research.

• • Fourier-Transform Infrared Analysis of Antibody Drugs

  Antibody drugs are a class of drugs that are artificially synthesized antibodies used to treat diseases by specifically binding to target molecules. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody-drug conjugates. Antibody drugs have demonstrated significant efficacy in treating various diseases such as cancer, autoimmune diseases, inflammatory diseases, immune regulation, and ophthalmic diseases.

• • Mass Cytometry Analysis of Cell Phenotypes

  The world of life is so wonderful, with each organism composed of an astonishing number of cells, and each type of cell having its own unique characteristics and functions. How to observe and understand the heterogeneity, cell phenotypes, and their differences has been a long-standing research direction for biologists. For this purpose, the field of biopharmaceuticals brings us a powerful tool - mass spectrometry flow cytometry technology.

• • Detection of Glycosylation Sites (N-glycan, O-glycan) in Recombinant Protein Vaccines

  Recombinant protein vaccines are a novel type of vaccine product produced using genetic engineering technology in organisms or cell systems. During the production process of these vaccines, glycosylation reactions may occur, where sugar chains are added to the N-site (e.g. asparagine) and O-site (e.g. serine or threonine) of the protein. Glycosylation is an important post-translational modification of proteins that affects their stability, solubility, biological activity, etc.

• • What Proteins Can Astral High-Resolution Mass Spectrometry Detect?

  Astral high-resolution mass spectrometry is a novel technological tool that has been widely used and achieved significant success in the field of biopharmaceuticals. Its main function is to provide protein analysis and accurately lock in protein mass spectrometry data. With its excellent performance, researchers can conduct in-depth studies on various types of proteins, promoting advances in biological science.

• • Determination of Isoelectric Point of Recombinant Protein Drugs

  Recombinant protein drugs refer to protein products derived from animals and plants through biotechnological research and development, which have certain biological activity and can prevent, treat, and diagnose diseases in humans, animals, and plants. Compared to small molecule drugs, recombinant protein drugs have advantages such as high activity, high specificity, and low toxicity, which makes them favored by researchers.