Resources

Proteomics Databases



Metabolomics Databases

• • Methods for Detecting Ubiquitination Levels and Their Pros and Cons

  With the continuous development in the field of biopharmaceuticals, the study of protein regulation mechanisms has become increasingly important. In this process, the detection of ubiquitination levels has become a key technique, helping scientists understand the functionality of the ubiquitin system and its association with protein degradation and cellular processes.

• • Exploring Stable Interactions and Structural Changes Between Proteins Through Disulfide Bond Detection

  The disulfide bond is one of the important stabilizing factors in protein structure, playing a key role in maintaining the structure and function of proteins. The formation and breakage of disulfide bonds can lead to changes in protein structure, thereby affecting their interactions and functions. With the development of protein research, the detection of disulfide bonds has become an important technique for exploring protein stability and structural changes.

• • Analysis of Polysaccharide Binding Sites and Binding Ratios in Conjugate Vaccines

  Combination vaccine, also known as conjugate vaccine, such as pneumococcal vaccine, is a complex vaccine composed of antigen proteins and polysaccharide structures. It belongs to a special category of vaccines. The working principle of the combination vaccine is to attach small molecule antigens (usually polysaccharides) to large molecule carrier proteins, which can often induce strong immune reactions.

• • How Does Phosphoproteomics Aid in Deciphering Key Codes of Metabolic Regulation?

  Cellular metabolism regulation is an important process for maintaining life activities, which involves complex signaling networks and regulatory mechanisms. In recent years, phosphoproteomics has been widely used as a powerful tool to study the mechanisms of cellular metabolism regulation.

• • Phosphoproteomics Deciphering the Phosphorylation Regulatory Mechanisms of Cell Signaling Transduction

  Cell signaling is an important process for maintaining cellular activities, regulating the physiological functions of cells through a series of signaling molecules and pathways. Among them, phosphorylation regulation mechanism plays a crucial role in cell signaling. Phosphorylation refers to the addition of phosphate groups (phosphorylation groups) to protein molecules, thereby altering their structure and function.

• • Phosphoproteomics Revealing Links Between Protein Degradation and Cell Function

  Cells are the basic units of life, and their normal functioning is crucial for maintaining the normal physiological activities of an organism. Proteins, as important components of cells, participate in almost all cellular regulatory processes. Phosphorylation is a common protein modification method, and through phosphorylation, the structure and function of proteins can be altered, thereby affecting important physiological processes such as cell signaling, metabolic regulation, and cell cycle.

• • How Does Phosphorylation Modulate Protein Folding and Redox Linkages?

  Protein is one of the most important molecules in living organisms and plays various functions within cells. However, the function of proteins is often regulated by their structure. Phosphorylation modification, as a common protein modification, plays an important role in regulating protein folding and redox processes.

• • Differences Between Glycosylation Modification and Identification in Research Focus and Method Selection

  In organisms, proteins are not only the most important functional molecules in cells, but also play crucial roles in various biological processes and signaling pathways. To enhance the functionality and diversity of proteins, cells undergo various modifications of proteins, among which glycosylation has received significant attention as an important protein modification.

• • Prospects of Phosphorylation Modifications in Drug Development

  With in-depth research on protein modifications, phosphorylation modification plays a crucial role in cellular regulation as an important signaling transduction mechanism. In recent years, phosphoproteomics analysis has gradually become a hot topic in drug development.

• • Glycan Profiling Facilitating Analysis of Protein-Glycan Interactions

  Glycan profiling, as one of the important techniques in the field of glycomics for biopharmaceuticals, is becoming a critical step in drug development. Many proteins on the cell surface and within cells undergo covalent attachment with glycans, forming glycosylation modifications. This type of modification not only regulates protein structure and function, but also has important effects on the stability, activity, and immunogenicity of biopharmaceuticals.