Resources
Proteomics Databases
Metabolomics Databases
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• Advances in Immunopeptidomics
Immunopeptidomics is a scientific discipline dedicated to studying peptide molecules integral to the immune system. This field aims to identify and quantify peptides involved in antigen presentation, immune surveillance, and the orchestration of immune responses. These peptides may be derived from various protein sources, including pathogen-derived proteins, endogenous self-proteins, and non-classical antigens. By investigating these molecules, researchers can deepen their understanding of immune syst......
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MALDI TOF MS is renowned for its high resolution, wide mass range, and rapid analytical capabilities. This technique determines the mass-to-charge ratio (m/z) of ions by measuring their flight time from the ion source to the detector. The unique approach of TOF-MS makes it a powerful tool in fields such as proteomics, metabolomics, and materials science. With ongoing technological advancements, the role of MALDI TOF MS has become increasingly pivotal in both basic research and applied sciences. The ......
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Matrix-assisted laser desorption/ionization time-of-flight (MALDI TOF mass spectrometry) is widely used in proteomics, metabolomics, and other molecular analysis fields. Due to its high sensitivity, broad dynamic range, and ability to cover a wide molecular weight range, MALDI TOF mass spectrometry has become an essential tool for the study of biomolecules. Initially developed by Karas and Hillenkamp in 1988, MALDI TOF mass spectrometry rapidly became a key component of modern mass spectrometry. It ex......
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• Analytical Chemistry Mass Spectrometry
Analytical chemistry mass spectrometry is a vital tool in chemical analysis, used for the separation, identification, and quantification of compounds. This technique relies on the mass analysis of ions, measuring their mass-to-charge ratio (m/z) to extract information about molecular mass and structure. Due to its exceptional sensitivity and specificity, analytical chemistry mass spectrometry is widely applied across fields such as chemistry, biochemistry, and drug development. The fundamental princ......
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• Molecular Weight from Mass Spec
Molecular weight from mass spec is an analytical technique based on mass spectrometry that precisely measures molecular mass. With its high sensitivity, resolution, and broad applicability, it has become an essential tool in modern life sciences and chemical research. This method is widely used in proteomics, drug development, biochemical analysis, and materials science, providing key insights into molecular structure, properties, and functions by analyzing mass characteristics. Principle of Molecul......
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• Intact Protein Quantification
Intact protein quantification is a technique used to analyze the content of intact protein molecules. This method directly quantifies proteins without the need for pre-treatment such as degradation or cleavage, making it especially valuable in proteomics research. By preserving the natural state of proteins, intact protein quantification retains important information, such as post-translational modifications, and offers unique insights for biomarker discovery, drug development, and the study of biolog......
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Mass determination is a high-precision analytical technique based on mass spectrometry, used to measure the mass of molecules or ions. As a crucial tool in modern science and technology, it is extensively applied across fields such as chemistry, biology, pharmacology, and materials science, offering essential support in exploring the molecular and atomic scale of the world. At the core of mass determination is the measurement of the mass-to-charge ratio (m/z) of charged ions using a mass spectromete......
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• Mass Spectrometry Molecular Weight
Mass spectrometry molecular weight determination is a technique used to determine the molecular weight of a molecule or ion by measuring its mass. This method is widely applied in fields such as biological sciences, chemistry, and materials science, where it aids researchers in determining the molecular weight of biomolecules and inferring their molecular structures. The technique relies on the use of a mass spectrometer, a highly sensitive and complex instrument capable of quickly and accurately iden......
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• Intact Mass Analysis of Antibodies
Intact mass analysis of antibodies is an analytical process used to comprehensively assess the structural integrity and consistency of antibody molecules in terms of their quality and structure. This analysis is essential in the development of antibody therapeutics, production quality control, and functional studies. With the growing use of antibody-based drugs in the treatment of cancer, autoimmune diseases, and infectious diseases, intact mass analysis of antibodies has become a central component of......
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• Analysis of Biomolecules Using Mass Spectrometry
Mass spectrometry is an efficient analytical technique extensively used in biomolecular research. The analysis of biomolecules using mass spectrometry involves measuring the mass-to-charge ratio of ions within a sample, providing researchers with the ability to elucidate complex biomolecular structures, identify compounds, and quantitatively analyze their concentrations. This method enables scientists to gain detailed insights into dynamic changes within biological systems at the molecular level. Ma......
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