Resources

Proteomics Databases



Metabolomics Databases

• • Methods for Determining Protein Purity

  Protein is an important biomolecule in organisms, and its purity directly affects the quality and efficacy of biopharmaceuticals. Therefore, accurate determination of protein purity is a crucial task in the field of proteomics in biopharmaceuticals. In purity determination, choosing the appropriate method is essential. This article will introduce several common determination methods.

• • Unveiling Protein Analysis Through Mass Spectrometry

  Mass spectrometry analysis, as an efficient proteomic technique, is widely used in areas such as biopharmaceutical development, biomarker identification, and disease research. Through mass spectrometry analysis, we can gain in-depth understanding of protein structure and function, providing strong support for biological and medical research.

• • What is SG in N-Glycosylation Modification in Mass Spectrometry?

  In the field of biopharmaceuticals, protein modification is no longer just a simple "decoration," but has become an important switch controlling life processes. Among them, N-glycosylation modification has become a widely studied focus.

• • Versatility of Liquid Phase Analysis Techniques in Proteomics

  In proteomics, liquid phase analysis techniques play a crucial role due to their wide range of applications and ability to provide rich information, which has greatly facilitated the rapid development of proteomics. High-performance liquid chromatography (HPLC) is the most common and fundamental method in liquid phase analysis. In proteomics, HPLC is mainly used for protein separation and purification.

• • Can Mass Spectrometry Reveal the 3D Structure of Proteins?

  Mass spectrometry is a technique that obtains structural information of compounds by measuring the ratio of molecular ion mass to quantity. In theory, this method should only be sensitive to the mass and charge of substances, not to their shapes and structures.

• • Differences and Connections Between Acetylation and Other Modifications

  Histone acetylation modification is a common post-translational modification of proteins in organisms. It refers to the transfer of acetyl groups from acetyltransferases (HATs) to lysine residues of histones through the transfer of energy. The differences and connections between acetylation and other modification methods reveal the secrets of life.

• • Investigation of Exosome Proteomics Detection Method

  Protein is the most fundamental molecular machinery in organisms, playing important roles in regulating cell functions, transmitting signals, and participating in biological processes. Accurate identification of protein structure and function is crucial for drug development and treatment strategies in the field of biopharmaceutical research. However, due to the complexity and diversity of proteins, their identification has always been one of the challenges faced by biologists.

• • Application of KEGG Pathway Analysis in Differential Protein Expression

  In proteomics, differential protein expression analysis has become a vital tool for understanding how biological systems respond and adapt to various environmental changes. KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis, a widely used bioinformatics method, helps researchers gain insights into complex protein and gene interaction networks by providing comprehensive functional annotations and pathway information.

• • Mechanism of KEGG Pathway Enrichment Analysis

  Pathway enrichment analysis is widely utilized in biological research to understand the functional roles of genes or proteins in various biological processes. KEGG (Kyoto Encyclopedia of Genes and Genomes) is one of the most commonly used bioinformatics resources for pathway enrichment analysis. KEGG pathway enrichment analysis reveals the enrichment of specific biological pathways in a gene set by comparing gene expression differences under different experimental conditions.

• • Advantages and Limitations of KEGG Pathway Analysis

  The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis is one of the widely used tools in bioinformatics and genomics research. It provides a systematic approach for exploring the relationships between genes and proteins within biological pathways and for investigating their roles in various biological processes. Through KEGG pathway analysis, researchers can identify and interpret the functional roles of genes or proteins within complex biological networks.