Resources

Proteomics Databases



Metabolomics Databases

• • PRM LC-MS Targeted Proteomics

  Proteomics is an essential approach in biological research for exploring protein functions and structures. Recently, PRM (Parallel Reaction Monitoring) coupled with LCMS (Liquid Chromatography-Mass Spectrometry) has emerged as a highly precise method for targeted protein analysis, enabling quantitative measurements of specific proteins within the proteome.

• • Differential Protein Analysis and Annotation in Proteomics

  Proteomics is the study of the large-scale expression, structure, and function of proteins. One of its crucial steps is differential protein analysis, which involves collecting protein samples, separating and identifying proteins, and performing quantitative and qualitative analyses. Finally, protein annotation is conducted to gather functional insights.

• • Targeted Quantitative Proteomics SRM

  Selected Reaction Monitoring (SRM) is a widely applied technique in quantitative proteomics. Owing to its exceptional sensitivity and quantitative accuracy, SRM is indispensable in various research domains. It is primarily utilized for the quantitative measurement and validation of specific proteins. The operating principle of SRM is based on detecting and quantifying target analytes via predefined target ions.

• • 3D Proteomics Sequencing

  Proteins are fundamental to life, performing essential functions such as catalyzing biochemical reactions, safeguarding the immune system, and facilitating molecular transport. Since protein structure is intrinsically linked to function, elucidating protein structures holds immense scientific significance and wide-ranging applications. One of the most advanced approaches in this field is three-dimensional (3D) structural proteomics.

• • What Is Single-Molecule Protein Sequencing Technology

  Single-Molecule Protein Sequencing (SMPS) is an emerging technology that enables the determination of protein amino acid sequences at the single-molecule level. This technique has promising applications in biology, drug development, and disease diagnostics. The Significance of Single-Molecule Protein Sequencing Technology: Over the past few decades, rapid advancements in DNA sequencing have significantly propelled progress in biological sciences. However, DNA sequencing alone does not provide direct........

• • N-Terminal Amino Acid Sequencer

  The N-terminal amino acid sequencer, also known as an amino acid sequence analyzer, is a device designed to determine the sequence of amino acids in proteins or peptides. This technology employs the Edman degradation method, which involves a series of chemical reactions to sequentially identify each amino acid from the N-terminal (amino terminus) of a protein or peptide. The operational foundation of the N-terminal amino acid sequencer lies in Edman degradation.

• • Amino Acid Sequence Variation Analysis

  Amino acids are the fundamental building blocks of proteins and play a crucial role in biological processes. Variations in amino acid sequences are key drivers for organisms adapting to environmental changes and undergoing evolution. This article discusses how to analyze amino acid sequence variations. Concept of Amino Acid Sequence Variation: Amino acid sequence variation refers to changes occurring in the amino acid sequences of a species over time.

• • Edman Degradation Service for Protein Sequencing

  Edman degradation service is an established method for determining the amino acid sequence of proteins. Originally developed by Pehr Edman in the 1950s, this technique remains a fundamental approach in proteomics research. The principle of Edman degradation involves a stepwise chemical process that sequentially removes amino acids from the N-terminus of a polypeptide chain, followed by identification of the released amino acids to determine the complete sequence.   In biomedical research, understandin......

• • Protein Seq

  Protein seq refers to the specific arrangement of amino acids in a protein within living organisms. Proteins are essential molecules that carry out nearly all cellular functions, including catalyzing biochemical reactions, providing structural support, regulating cellular processes, and participating in signal transduction. Proteins are large biomolecules composed of 20 standard amino acids, linked by peptide bonds. The sequence of these amino acids defines the protein seq, which is crucial for unders......

• • C-Terminal Protein Sequencing

  The primary goal of C-terminal protein sequencing is to determine the amino acid composition and sequence at the carboxyl terminus of a protein. Proteins are macromolecules consisting of amino acids covalently linked by peptide bonds, and their biological functions and physicochemical properties are largely dictated by their amino acid sequences. Information on the C-terminal sequence is crucial for understanding protein function, post-translational modifications, and degradation pathways. The biologi......