R5P Analysis Service

Ribose-5-phosphate (R5P) is a critical metabolite in the pentose phosphate pathway (PPP), playing a fundamental role in cellular metabolism. R5P is a phosphorylated sugar, derived from the breakdown of glucose-6-phosphate via the oxidative branch of the PPP. It serves as a precursor for the synthesis of nucleotides and nucleic acids, as well as the regeneration of NADPH, which is crucial for maintaining cellular redox balance and supporting biosynthetic processes. The pentose phosphate pathway, in which R5P is involved, is vital for managing oxidative stress, synthesizing nucleotides, and providing metabolic intermediates for various anabolic processes.

 

Research into R5P has shed light on its significance in both normal physiology and disease states. Dysregulation of the pentose phosphate pathway, particularly R5P levels, has been associated with metabolic disorders, cancer, and neurodegenerative diseases. The availability of R5P can influence cellular proliferation rates due to its central role in nucleotide biosynthesis, making it a key target for studies in cancer metabolism. Additionally, R5P plays a role in immune cell function and pathogen defense, further highlighting its importance across multiple biological systems.

 



 

Figure 1. The Structure of R5P

 

MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.

 

At MtoZ Biolabs, our team of highly skilled scientists and specialists is equipped with state-of-the-art mass spectrometry technology to provide comprehensive R5P analysis. We provide a state-of-the-art R5P Analysis Service using high-resolution mass spectrometry. Our service delivers precise quantification and profiling of R5P in various biological samples, offering valuable insights into its metabolic roles.

 

Analysis Workflow

 



 

Service Advantages

1. Advance Analysis Platform

MtoZ Biolabs established an advanced R5P analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.

 

2. One-Time-Charge

Our pricing is transparent, no hidden fees or additional costs.

 

3. High-Data-Quality

Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all R5P analysis service data providing clients with a comprehensive data report.

 

4. Fast Turnaround

The process from sample handling to report generation is efficient, shortening the analysis cycle.

 

Applications

Our R5P analysis service is applicable in various fields, including but not limited to:

• Biomarker Discovery
• Drug Discovery and Development
• Metabolic Disease Research

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on R5P

4. Raw Data

5. Custom Analysis Report

 

At MtoZ Biolabs, we are dedicated to providing you with the most reliable and comprehensive R5P analysis service. Contact us today to discuss your project requirements.