Pregnenolone Analysis Service

Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is a crucial precursor in steroid biosynthesis, primarily derived from cholesterol within the body. It serves as the foundation for the synthesis of various hormones, including those involved in the nervous system, immune response, and reproductive health. Given its pivotal role in multiple physiological processes, pregnenolone is also closely associated with the pathogenesis of numerous conditions, such as neurodegenerative disorders, mood disorders like depression, and certain hormone-related cancers. Therefore, accurate measurement of pregnenolone levels is of paramount importance in both clinical research and drug development.

 

Figure 1. Molecular Structure of Pregnenolone

 

MtoZ Biolabs offers Pregnenolone Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in P5 detection.

 

Analysis Workflow

 



 

Service Advantages

1. Advance Analysis Platform: MtoZ Biolabs established an advanced targeted metabolomics analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all targeted metabolomics analysis data providing clients with a comprehensive data report.

4. Multi-Sample Compatibility: Our platform supports a wide variety of biological samples, including cells, tissues, blood, and bodily fluids, providing flexibility to accommodate diverse research demands.

5. Customized Service: Tailored to the specific research needs of our clients, we offer flexible experimental design and personalized data analysis to ensure the achievement of research goals to the fullest extent.

 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Applications

1. Investigating the role of P5 in conditions such as Alzheimer's disease and Parkinson's disease.

2. Monitoring changes in P5 and its metabolites in endocrine conditions like polycystic ovary syndrome and adrenal gland disorders.

3. Exploring the potential of P5 as a therapeutic agent in mood disorders, including depression and anxiety.

4. Assessing the involvement of P5 in hormone-dependent cancers, such as breast and prostate cancers.

5. Utilizing P5 and its derivatives in drug candidate development, focusing on bioactivity and metabolic profiling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Pregnenolone

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into pregnenolone's extensive physiological roles through top-tier analytical techniques and expert services.