Polarimeter Analytical Service

A polarimeter is an optical analytical instrument designed to measure the angle of rotation that occurs when polarized light passes through optically active substances. This phenomenon arises from the interaction between chiral molecules and polarized light, causing rotation of the plane of polarization. By precisely measuring the angle of rotation, it is possible to determine key parameters such as specific rotation, concentration, and purity, thereby providing critical insights into the composition and structural characteristics of substances. Polarimeter has a broad range of applications, spanning pharmaceuticals, food, chemicals, and research. It is a core technique for characterizing chiral compounds and carbohydrates.

 



Figure 1. Operating Principle of an Optical Polarimeter

 

Supported by an advanced optical testing platform and a team of scientific experts, MtoZ Biolabs offers Polarimeter Analytical Service to research institutions, pharmaceutical enterprises, and food manufacturers. Our service provides reliable and accurate optical rotation measurements and data interpretation. It can be applied to unknown compound identification, purity testing, routine quality control, and high-precision scientific research.

 

Services at MtoZ Biolabs

The core of polarimetric analysis lies in measuring the rotation angle induced by a sample on polarized light. A light source emits unpolarized light, which is converted into linearly polarized light via a polarizer. This polarized light passes through a sample cell and is subsequently analyzed by an analyzer that detects the degree of rotation. Based on the observed angle, along with concentration and path length, specific rotation or sample concentration can be calculated.

 

Within the polarimeter analytical service provided by MtoZ Biolabs, we offer:

✅ Optical rotation measurement: High-precision determination of the optical activity of samples.

✅ Specific rotation calculation: Accurate computation of specific rotation values using angle, concentration, and path length.

✅ Concentration and purity testing: Rapid determination of concentration and purity for substances with known specific rotation.

✅ Enantiomeric ratio analysis: Evaluation of enantiomer distribution in chiral mixtures and assessment of optical activity in chiral drugs.

 

Our polarimeter analytical service supports a wide range of samples, including carbohydrates, amino acids, pharmaceutical raw materials, essential oils, and diverse organic compounds, meeting both fundamental research and applied development needs.

 

Analysis Workflow

1. Sample preparation: Clients submit optically active samples according to requirements.

2. Instrument setup: Adjustment of light source, polarizer, and analyzer to ensure stable operation.

3. Measurement: Optical rotation is measured using a polarimeter with repeated trials for accuracy.

4. Data calculation: Specific rotation or concentration is calculated based on the measured angle, path length, and concentration.

5. Result delivery: Data is compiled into a report including measurement results and interpretations.

 

Service Advantages

1. High data reliability

Using high-performance polarimetric platforms, MtoZ Biolabs ensures stable operation under diverse sample conditions. Multi-point measurement and calibration guarantee repeatability and comparability of results.

 

2. Broad sample compatibility

The polarimeter analytical service supports carbohydrates, amino acids, essential oils, pharmaceutical intermediates, and more. Whether analyzing dissolved solids or raw liquids, our approach adapts to sample diversity and minimizes bias.

 

3. Standardized analytical workflow

We emphasize traceability and standardization at every step. Rigorous quality control ensures authenticity and reliability of results, free from operator-induced interference.

 

4. Balanced support for research and industry

Whether for academic research or industrial quality control, MtoZ Biolabs provides tailored solutions. Our polarimeter analytical service satisfies the demand for high accuracy in research and efficiency in industrial batch testing.

 

5. Comprehensive reporting

Results include not only numerical outputs but also charts, calculation details, and interpretations. Clients gain clear insights for publication, process optimization, or product validation.

 

Applications

✔️ Pharmaceutical industry: Determination of purity and optical activity in raw materials and finished drugs to ensure compliance with quality standards.

✔️ Food and beverage industry: Measurement of carbohydrate concentration and purity in syrups, beverages, and dairy products for quality control.

✔️ Essential oils and fragrance industry: Evaluation of optical properties of natural products to ensure authenticity and consistency.

✔️ Chemical industry: Analysis of natural and synthetic polymers, additives, and organic compounds.

✔️ Research institutions: Identification of unknown substances, tracking of reaction kinetics, and molecular structure studies.

 

FAQs

Q1: Can mixtures be analyzed?

A: Yes. For enantiomeric mixtures, polarimetry can indirectly estimate ratios through rotation measurements. For more complex mixtures, complementary methods may be required.

 

Q2: What is the typical turnaround time of polarimeter analytical service?

A: Reports are usually delivered within 3–5 working days after sample receipt. The exact timeframe depends on sample quantity and complexity.

 

Sample Submission Suggestions

1. Sample types: Transparent, homogeneous solutions free of suspended particles or bubbles.

2. Storage conditions: Most samples can be shipped at room temperature. Sensitive samples should be shipped refrigerated or frozen.

3. Sample volume: A minimum of 5 mL is recommended to ensure repeat measurements.

4. Information required: Please provide compound category, estimated concentration, and solvent type.

 

Deliverables

1. Raw optical rotation measurement data

2. Calculated specific rotation or concentration results

3. Data interpretation and conclusions

4. Comprehensive report (including methodology, measurement conditions, and result analysis)

 

Polarimeter analytical service is not only an essential tool for scientific exploration but also a reliable solution for industrial quality control. With advanced instrumentation and standardized workflows, MtoZ Biolabs delivers high-quality, reproducible polarimetric analysis. Whether for fundamental research or applied development, we are your trusted partner.

 

Contact us today to learn more about our customized polarimeter analytical service and accelerate the success of your research and industrial projects.