Palmitoyl Ethanolamide Analysis Service

Palmitoyl ethanolamide (PEA) is an endogenous fatty acid amide formed by the connection of a long-chain saturated fatty acid (palmitic acid) and ethanolamine through an amide bond. Its structural characteristic is the combination of a 16-carbon long-chain fatty acid with ethanolamine. In the body, PEA is metabolized by enzymes such as N-acylethanolamine hydrolyzing acid amidase (NAAA) and fatty acid amide hydrolase (FAAH). Its metabolic process includes hydrolysis into palmitic acid and ethanolamine, which are then further metabolized into other products. PEA has a relatively short half-life in the body, and its metabolic rate is influenced by individual differences, enzyme activity, and health status. The levels of PEA and its metabolites in the body are closely associated with various diseases, including chronic pain, inflammatory diseases, neurodegenerative diseases, and immune system disorders. By analyzing the concentrations of PEA and its metabolites in biological samples, it can serve as a biomarker for these disease states, helping in the diagnosis and monitoring of disease progression. For instance, changes in PEA levels in cases of inflammation or nerve injury may reflect the severity of the condition or the response to treatment.

 



Figure 1. The Structure of Palmitoyl Ethanolamide

 

The analysis of PEA and its metabolites can provide support for new drug development and clinical research. By measuring the levels of PEA and its metabolites, the impact of new drugs or therapeutic approaches on PEA metabolism can be evaluated, and new metabolic pathways or potential targets can be identified. This helps in developing more effective drugs and therapeutic strategies, particularly in the areas of pain management, neuroprotection, and immune regulation. MtoZ Biolabs provides professional, efficient, and customized palmitoyl ethanolamide (PEA) analysis services, helping clients achieve significant advancements in basic research, clinical diagnosis, new drug development, personalized medicine, and health product development.

 

Analysis Workflow

 



 

Service Advantages

1. Continuously refined protocols and cutting-edge analytical tools  

 

2. Expert experimental planning  

 

3. Rapid processing times  

 

4. Exceptional precision, selectivity, and sensitivity

 

Applications

• Qualitative analysis of PEA metabolites
• Quantitative analysis of PEA content
• Provide basis for potential therapeutic applications

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues and other biological samples. For each sample, it is required to select more than 3 materials under the same condition.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Sample Preservation

Store the sample at -80°C to maintain stability.

 

Note: Please provide detailed information on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Palmitoyl Ethanolamide

4. Raw Data

5. Custom Analysis Report

 

By leveraging our sophisticated palmitoyl ethanolamide analysis service, we aim to enhance your research and product development processes by delivering accurate and reliable results.