Obesity Related Immune Factors Analysis Service

Obesity is a systemic disease, not only does it lead to changes in body shape, but it also brings along various diseases and complications, affecting an individual's overall health. Common complications, such as hyperglycemia, hyperlipidemia, and hypertension, are medically termed as "metabolic syndrome". The fluid factors secreted by adipose tissue propel the development of metabolic syndrome and vascular diseases. These substances include leptin, adiponectin, resistin, TNF-α, IL-6, PAI-1, angiotensinogen, C-reactive protein (CRP), etc. Other cytokines such as adhesion molecules ICAM-1, VCAM-1, and E-selectin are also associated with endothelial cell activation and atherosclerosis in obese patients.

 



Figure 1. The Health Risks of Obesity

 

MtoZ Biolabs utilizes flow cytometry to simultaneously quantify cytokines and proteins related to obesity and its complications, offering higher sensitivity and a broader detection range. The table below lists the cytokines detectable in human samples, and MtoZ Biolabs also provides detection for other species, consultation is welcome.

 

Obesity-Related Immune Factor Detection — Flow Cytometry



Figure 2. Obesity-Related Immune Factors Multi-Cytokine Flow Cytometry Kit for Human Samples

 



Figure 3. Obesity-Related Immune Factors Single-Cytokine Flow Cytometry Kit for Human Samples

 

Sample Submission Requirements

1. A Minimum of 25 µL of Sample is Required, Compared to the 50 µL or 100 µL Needed for Conventional ELISA

2. Applicable to Serum, Plasma, Cell Culture Supernatants, and Various Bodily Fluids

3. Bodily Fluid Samples must be Stored at -80 ℃ and Shipped with Dry Ice

 

Deliverables

In the technical report, MtoZ Biolabs will provide you with detailed technical information, including:

1. Experimental Procedures

2. Raw Data (Fluorescence luminescence Spectrum)

3. Technical Report

4. Absolute Content of Each Detection Indicator (Excel Spreadsheet)