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    Nasopharyngeal Carcinoma (NPC) Tissue Glycosylated Peptide Analysis

      Nasopharyngeal carcinoma is a malignant tumor originating from the nasopharynx area. The incidence of nasopharyngeal carcinoma varies significantly worldwide. Despite the current treatment methods, including radiotherapy, chemotherapy, and surgery, the prognosis of nasopharyngeal carcinoma is still limited by the degree of disease progression at diagnosis and the choice of treatment methods. Therefore, finding biomarkers for early diagnosis and treatment is particularly important. Glycosylation, as a common form of post-translational modification of cell surface proteins and secreted proteins, has been proven to play a key role in the development of various cancers. Research on nasopharyngeal carcinoma has always been an important branch in the field of cancer research. Analyzing the glycosylated peptides in nasopharyngeal carcinoma tissues is an important way to understand its pathogenesis and find potential therapeutic targets.

       

      The Significance of Research on Glycosylated Peptides in Nasopharyngeal Carcinoma

      The analysis of glycosylated peptides helps us to understand the biological characteristics of nasopharyngeal carcinoma cells more deeply. For example, certain specific glycosylation patterns may be associated with the invasion and metastasis ability of tumor cells. By analyzing these glycosylated peptides in detail, researchers can identify those glycoproteins that play a key role in the development of nasopharyngeal carcinoma. These glycoproteins may become new biomarkers or therapeutic targets.

       

      Services at Mtoz Biolabs

      Currently, the analysis of glycosylated peptides mainly depends on mass spectrometry. Mass spectrometry is a powerful analytical tool that can accurately identify the molecular composition and structure of samples. In the research of nasopharyngeal carcinoma, mass spectrometry can be used to quantitatively and qualitatively analyze the glycosylated proteins in tumor tissues, revealing their glycosylation status and dynamic changes.

       

      The company has developed a method for complete glycosylation analysis of specific glycoproteins based on the high-resolution mass spectrometry platform of liquid chromatography, providing you with high-quality one-stop glycosylated peptide analysis services, accurately analyzing glycosylation modification categories, glycosylation site modification efficiency, and the ratio of various sugar types at the glycosylation site.

       

      1. Experimental Instruments

      (1) NanoLC

      Vanquish NEO

       

      (2) MS

      Orbitrap Fusion Lumos With ETD

       

      2. Technical Advantages

      (1) High Sensitivity Detection

      By using advanced liquid chromatography-mass spectrometry (LC-MS) technology, the glycosylated peptides in nasopharyngeal carcinoma tissues can be accurately identified and quantified. This technology can detect extremely low-abundance glycosylation modifications, providing the possibility of discovering potential cancer biomarkers.

       

      (2) Broad Coverage of Glycosylation Types

      Our technology platform can analyze multiple types of glycosylation, including N-linked and O-linked glycosylation. This means that the role of glycosylation in the occurrence and development of nasopharyngeal carcinoma can be comprehensively evaluated, providing more comprehensive biological information.

       

      (3) In-Depth Data Analysis

      In addition to high-precision glycosylated peptide identification, we also provide in-depth bioinformatics analysis, including glycosylation site analysis, glycosylation pattern recognition, and analysis related to cancer progression. This can help reveal the biological significance of glycosylation in the occurrence and development of nasopharyngeal carcinoma.

       

      (4) Strict Quality Control

      Strict quality control is implemented throughout the analysis process to ensure the accuracy and repeatability of the data. Each step is executed according to international standards to ensure the scientific and reliability of the research results.

       

      3. Case Demonstration

      The expert team at MtoZ Biolabs has deep professional knowledge and rich experimental experience. We are committed to providing customers with high-quality, high-precision glycosylated peptide analysis services through continuous technological innovation and optimization. MtoZ Biolabs looks forward to becoming your trusted partner. You are welcome to consult us at any time for more service information and technical support.

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