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    NA Analysis Service

      NA (Nicotinic acid) is an important water-soluble vitamin with a chemical structure consisting of a pyridine ring attached to a carboxyl group (-COOH). It can be obtained through dietary sources (such as meat, fish, nuts, and whole grains) or synthesized in the body from tryptophan. In terms of biological activity, NA plays a crucial role in energy metabolism, serving as a precursor for the coenzymes NAD and NADP, which are involved in redox reactions within cells. Additionally, it has positive effects on the nervous system and skin health. Metabolites of NA include nicotinamide and nicotinic acid amide, which exhibit various biological activities, including antioxidant and anti-inflammatory properties, as well as regulating blood lipids. Analyzing the levels of NA and its metabolites in plants and biological samples is significant for several reasons. Firstly, it helps assess the nutritional value of foods and medicinal plants, ensuring that health needs are met for humans and animals. Secondly, monitoring changes under different physiological conditions aids in understanding its role in disease prevention and treatment, particularly in research related to cardiovascular diseases and metabolic syndrome. These analyses provide a scientific basis for developing relevant nutritional and therapeutic strategies.

       

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      Figure 1. The Structure of NA

       

      MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Our NA analysis service is based on liquid chromatography-mass spectrometry (LC-MS), a powerful tool for the identification and quantification of NA in various biological samples. This service aims to facilitate your research on the bioactivity of NA and its potential applications in pharmaceutical and nutraceutical industries.

       

      Analysis Workflow

       

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      Service Advantages

      • Accuracy: We ensure highly accurate quantification of NA and its metabolites.
      • Comprehensive Identification: We provide comprehensive and precise identification of various NA metabolites.
      • Experienced Team: Our team of skilled professionals ensures high-quality data analysis and robust technical support.
      • Quick Turnaround: We strive to provide results in a timely manner without compromising on quality.

       

      Applications

      • Pharmacology Research: To explore therapeutic properties of NA.
      • Product Development: To quantify and assess the quality of NA in health supplements or pharmaceutical products.
      • Biomedical Research: To study the metabolism of NA in various biological systems.

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples.

       

      More than three materials with the same condition for each sample are required.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to maintain stability.

       

      Deliverables

      1. Detailed Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on NA

      4. Raw Data

      5. Custom Analysis Report

       

      Through our NA analysis service, we aim to facilitate your research and product development processes by providing accurate and reliable results. Feel free to contact us for further queries.

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