N6,N6-dimethyladenosine Analysis Service

    N6,N6-dimethyladenosine is a modification of adenosine frequently found at the transcription start site of mRNA and possesses a crucial role in stabilizing mRNA structures and enhancing translation efficiency. N6,N6-dimethyladenosine is most commonly found in eukaryotes and is involved in diverse biological processes, including mRNA stability, protein synthesis, and cell differentiation. The dysregulation of N6,N6-dimethyladenosine has been linked to several pathological circumstances, such as neurological disorders, cancer, and cardiovascular diseases, making it a potential therapeutic target.

     

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    Figure 1. The Structure of N6,N6-dimethyladenosine

     

    The modulation of N6,N6-dimethyladenosine levels in mRNA can profoundly affect cellular function, elucidating the critical role of N6,N6-dimethyladenosine in modulating gene expression. Studying N6,N6-dimethyladenosine can shed light on the complex interplay between RNA metabolism and disease progression, offering new avenues for therapeutic intervention.

     

    MtoZ Biolabs is an experienced bioanalytical company offering a comprehensive portfolio of services, among them the N6,N6-dimethyladenosine Analysis Service. We use ultra-high-resolution mass spectrometry for the detection and quantification of N6,N6-dimethyladenosine in various biological samples. Our advanced techniques allow us to provide an in-depth profile of N6,N6-dimethyladenosine in a highly accurate and reproducible manner.

     

    Analysis Workflow

     

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    Service Advantages

    • Extensive experience in various biological sample preparation techniques
    • State-of-the-art mass spectrometry platforms
    • Professional standard operating procedure
    • Highly sensitive and reliable analysis
    • Rapid turnaround time and competitive pricing Customized service

     

    Applications

    • Biomarker identification in disease research
    • Investigation of N6,N6-dimethyladenosine metabolism pathways
    • Pharmaceutical development
    • Diagnostic research in relevant disorders

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Storage and Shipping

    Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

     

    Note: Please provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on N6,N6-dimethyladenosine

    4. Raw Data

    5. Custom Analysis Report

     

    At MtoZ Biolabs, our N6,N6-dimethyladenosine Analysis Service is designed to provide you with the most accurate and comprehensive data for your studies. Let us be your partner in advancing your research.

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