N6-methyladenosine Analysis Service
- State-of-the-art LC-MS/MS platforms allow us to accurately and reliably quantify m6A in various types of samples.
- A team of experts in mass spectrometry and metabolomics provides professional data analysis and interpretation.
- One-stop service from sample preparation, LC-MS/MS analysis to data analysis, saving your time and efforts.
- Competitive price with high-quality service.
- Investigation of m6A modification landscape in various diseases.
- Exploration of the function of m6A in physiological and pathological processes.
- Drug target discovery and biomarker development.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
N6-methyladenosine (m6A) is a modification occurring at the N6 position of adenosine. It is the most prevalent and abundant internal modification in eukaryotic mRNA and long non-coding RNA. m6A modification is a reversible process regulated by "writers" (methyltransferases), "erasers" (demethylases), and "readers" (proteins that recognize m6A modification). m6A plays crucial roles in various physiological and pathological processes, such as RNA stability and degradation, splicing, export, localization, translation, and secondary structure formation.
Figure 1. m6A Modification Occurs in Consensus DRACH Motifs of Cellular and Viral RNAs
m6A modification has been implicated in a variety of diseases including cancer, neurological disorders, and cardiovascular diseases. Therefore, understanding the global alteration of m6A modification landscape and the functional consequences is of great interest in both basic biological research and clinical applications.
At MtoZ Biolabs, we provide comprehensive N6-methyladenosine analysis service employing LC-MS/MS, with the features of high sensitivity, high specificity, and high-throughput. Our m6A analysis service can help you to thoroughly investigate the characteristic and function of m6A, thus facilitating your research in RNA epigenetics.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on N6-methyladenosine
4. Raw Data
5. Custom Analysis Report
If you have any questions or special requirements, please feel free to contact us. We look forward to working with you to advance your research.
How to order?
