MtoZ Biolabs Advanced N-Terminal Sequencing Service

The N-terminal of a protein marks the beginning of its expression and is integral to regulating subcellular localization, degradation, and turnover. MtoZ Biolabs offers high-quality N-terminal sequencing service through an advanced platform that integrates Edman degradation with mass spectrometry, which is suitable for a variety of sample types, including but not limited to proteins, peptides, antibodies, vaccines, recombinant proteins, etc.

Why Choose MtoZ Biolabs

MtoZ Biolabs' N-terminal sequencing service combines Edman degradation and mass spectrometry to achieve precise N-terminal analysis. This approach effectively addresses scenarios where the N-terminal is blocked or modified (PTM), providing researchers with comprehensive analytical solutions.

1. Edman Sequencing

Delivers accurate N-terminal sequence information by sequentially cleaving amino acid residues from the protein's N-terminal.

2. Mass Spectrometry Analysis

Overcomes challenges related to N-terminal blocking and modifications (PTM), offering detailed sequence validation and information on modification sites.

In this service, protein sequence is not restricted by sample types, N-terminal blockage, and PTMs. Protein N-T sequences can be accurately analyzed by Edman sequencing, whereas, the N-terminal blockage and PTMs can be analyzed by mass spectrometry.