Lysophospholipids Analysis Service
- LPA: Involved in regulating cell proliferation, migration, and angiogenesis, serving as a key signaling molecule in inflammation, cancer, and wound healing.
- LPC: Actively participates in inflammation, atherosclerosis, and demyelinating disorders, and is frequently studied in diseases such as multiple sclerosis.
- LPE: Modulates apoptosis and lipid metabolism, with implications in metabolic diseases and cancer.
Lysophospholipids (LPLs) are metabolites generated by phospholipase A2 from phospholipids, and are widely distributed in cell membranes due to their distinctive amphiphilic nature, with one hydrophilic and one lipophilic end. This unique structure enables lysophospholipids to be crucial in various biological processes, such as membrane remodeling, signal transduction, and inflammatory responses. With enhanced hydrophilicity compared to their precursor phospholipids, lysophospholipids are highly efficient in emulsification and micelle formation, offering distinct advantages in lipid digestion and absorption.
In industrial applications, LPLs are predominantly derived from soybean phospholipids, produced through specific enzymatic hydrolysis methods. The different structural types of LPLs, including lysophosphatidic acid (LPA), lysophosphatidylcholine (LPC), and lysophosphatidylethanolamine (LPE), play specialized roles across various physiological and pathological processes:
Makide, K. et al. J. Lipid Res, 2014.
Figure 1. Molecular Structures of Lysophospholipids
MtoZ Biolabs offers highly sensitive Lysophospholipids Analysis Servic using state-of-the-art liquid chromatography-tandem mass spectrometry (LC-MS/MS) technology. Our services cover a comprehensive range of LPLs, providing researchers with critical insights into their roles in neurological, cardiovascular, metabolic, and cancer-related studies.
Analysis Workflow
Service Advantages
Why Choose MtoZ Biolabs?
1. Advance Analysis Platform: MtoZ Biolabs established an advanced targeted metabolomics analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all targeted metabolomics analysis data providing clients with a comprehensive data report.
4. Multi-Sample Compatibility: Our platform supports a wide variety of biological samples, including cells, tissues, blood, and bodily fluids, providing flexibility to accommodate diverse research demands.
5. Customized Service: Tailored to the specific research needs of our clients, we offer flexible experimental design and personalized data analysis to ensure the achievement of research goals to the fullest extent.
Sample Submission Requirements
Deliverables
What Could be Included in the Report?
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment
4. Data Analysis, Preprocessing, and Estimation
5. Bioinformatics Analysis
6. Raw Data Files
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details!
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