Lignans Analysis Service | UPLC-MRM/MS

Lignans are a class of naturally occurring compounds with broad biological activities. They can be found in over 60-70 plant families and have been extracted from various plant parts, such as roots, rhizomes, stems, bark, leaves, seeds, and fruits. Lignans share a common 2,3-dibenzylbutane skeleton, but exhibit a variety of structures. Lignans are used in different foods, including dairy products and baked goods. After ingestion, these lignan-containing foods are metabolized in the gut, leading to the production of numerous beneficial active metabolites. Mass spectrometry is a highly sensitive analytical technique that can detect, identify, and quantify various plant lignans and their metabolites, even at low abundances, by measuring their mass and characterizing their chemical structures. Mass spectrometers are often coupled with gas chromatography (GC) or liquid chromatography (LC) to efficiently separate organic molecules from complex samples. Comprehensive analysis of plant lignan content and its metabolites helps to elucidate the changes in lignan levels at different stages of plant development and the potential metabolic pathways of lignans.

 



Figure 1. Chemical Structures of of Some Prominent Lignans

 

MtoZ Biolabs proudly offers a robust Lignans Analysis Service, with its superior high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) platform and seasoned metabolomics team. Our service provides a thorough Lignans analysis with remarkable sensitivity and accuracy.

 

Analysis Workflow

 



 

Service Advantages

1. Continuously Updated. At MtoZ Biolabs, we maintain a comprehensive laboratory network staffed with professional technicians, offering reliable plant-targeted metabolomics services and providing real-time updates on industry developments.

 

2. One-Stop Service. Our laboratory is equipped to meet the needs of clients seeking third-party testing services or wishing to outsource their monitoring and analysis projects, delivering personalized one-on-one, one-stop service.

 

3. Professional and Reliable. MtoZ Biolabs conducts warfarin analysis under strict quality, health, safety, and ethical control standards, and has earned multiple industry certifications, ensuring the highest level of professionalism and reliability.

 

Applications

• Qualitative and quantitative analysis of Lignans and its metabolites.
• The pharmacokinetic study of Lignans as well as safety and efficacy assessment.
• Quality control of food and drugs containing Lignans.
• Therapeutic efficacy study and mechanistic exploration.

 

Sample Submission Requirements

1. Sample Types

• Serum, plasma, urine, tissues, and other biological samples, food, drugs.
• At least 3 samples of the same condition for each type.

 

2. Sample Volume

• At least 200 μL of liquid sample
• At least 200 mg of animal tissues
• At least 1 g plant tissues

 

3. Sample Preservation

Store at -80°C for sample stability.

 

Note: Provide details on sample collection and protection.

 

Deliverables

1. Experimental Procedures

2. Key Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Lignans

4. Raw Data

5. Custom Analysis Report

 

With our Lignans analysis service, we endeavor to accelerate your research and product development by delivering accurate and dependable data.