Laser Diffraction Particle Size Analysis Service
- Sample Types: Powders, slurries, emulsions, and similar particulate samples.
- Sample Amounts: 10 mg-5 g. The required sample amount depends on the analysis type and particle size range.
- Particle Size Range: Suitable for particles from 0.1 to 1,000 micrometers.
Particle size distribution is a critical attribute in a wide range of industries, including pharmaceuticals, food science, cosmetics, chemicals, and materials research. Precise knowledge of particle size is essential for understanding product performance, stability, solubility, flow behavior, and processing characteristics. MtoZ Biolabs offers professional Laser Diffraction Particle Size Analysis Service to provide accurate, reproducible, and detailed measurements of particle size distributions. This service is designed to help clients optimize formulations, ensure quality control, and meet regulatory requirements.
Laser Diffraction Particle Size Analysis Service can measure particles across a broad size range, from submicron (0.1 μm) to millimeter scale (1000 μm). It enables rapid analysis of both wet and dry samples with high reproducibility, making it an ideal choice for diverse materials such as powders, suspensions, emulsions, and granular formulations. By employing advanced optical and computational methods, MtoZ Biolabs delivers precise particle size profiles that support research, development, and manufacturing applications.
Technical Principles
Laser diffraction particle size analysis is based on the principle that particles scatter light at angles inversely proportional to their size. Smaller particles scatter light at larger angles, while larger particles scatter light at smaller angles. By directing a laser beam through a sample and measuring the resulting scattering pattern, the system calculates particle size distribution using established mathematical models, such as Fraunhofer theories.
Source: https://www.researchgate.net/figure/Schematic-of-laser-diffraction-particle-size-analysis-method_fig3_385584250
Figure 1. Schematic of Laser Diffraction Particle Size Analysis Method
The laser diffraction particle size analysis technique can be applied to both dry powders and liquid suspensions. In dry mode, particles are dispersed using an airflow system, while in wet mode, particles are suspended in a suitable liquid to minimize agglomeration. Advanced detectors capture the scattered light at multiple angles, allowing accurate characterization of polydisperse samples. This capability enables detailed insights into sample uniformity, the presence of fines or coarse fractions, and overall particle morphology.
Analysis Workflow
Applications
MtoZ Biolabs' Laser Diffraction Particle Size Analysis Service supports a wide variety of applications:
1. Pharmaceuticals
Characterization of active pharmaceutical ingredients, excipients, and granules to ensure proper dissolution, bioavailability, and compressibility.
2. Food and Nutrition
Analysis of powders, starches, and other particulate ingredients to maintain texture, solubility, and flow properties.
3. Cosmetics
Quality control of powders, pigments, and emulsions to ensure consistent performance and product stability.
4. Chemical and Materials Science
Particle characterization of pigments, catalysts, and raw materials to optimize reactivity, processing, and product uniformity.
5. Nanotechnology
Measurement of submicron particles, nanoparticles, and colloids for research and development purposes.
Sample Submission Suggestions
Clients are encouraged to contact MtoZ Biolabs before submission for tailored preparation guidelines and testing recommendations.
Service Advantages
☑️ Advanced laser diffraction instruments and multi-angle detectors for precise measurement
☑️ Experienced experts providing tailored solutions for diverse industries
☑️ Flexible testing modes accommodating both wet and dry samples
☑️ Comprehensive reports with actionable insights for formulation, QC, and regulatory support
☑️ Commitment to high-quality, reproducible, and reliable analytical results
MtoZ Biolabs leverages advanced laser diffraction instrumentation, tailored measurement protocols, and expert analysis to provide accurate and detailed particle size characterization for a wide range of materials. Free project evaluation, welcome to learn more details!
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