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    L-Norvaline Analysis Service

      L-Norvaline (chemical formula: C₅H₁₁NO₂) is an amino acid classified as a non-essential amino acid. Its molecular structure consists of an amino group (-NH₂), a carboxyl group (-COOH), and a side chain, which is an isomeric pentyl group. This makes it similar to the standard L-valine, but with an additional methyl group. L-Norvaline exhibits certain biological activity, particularly in inhibiting nitric oxide synthase, which may positively influence vasodilation and enhance exercise performance. In exercise physiology, L-norvaline is considered to improve muscle performance and endurance; analyzing its changes before and after exercise can help evaluate the effectiveness of sports supplements. In the body, L-norvaline is primarily metabolized through transamination and decarboxylation reactions. It can be converted into other amino acids, participating in protein synthesis and metabolic processes. Metabolomics analysis of L-norvaline can reveal its metabolic pathways within the body, helping to understand its interactions with other amino acids and metabolites. This is essential for identifying key metabolic pathways and their variations in physiological and pathological states.

       

       

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      Figure 1. The Structure of L-Norvaline

       

      The content of L-norvaline is typically quantified using analytical methods such as high-performance liquid chromatography (HPLC), gas chromatography (GC), or mass spectrometry (MS). These methods provide high sensitivity and accuracy, suitable for measuring L-norvaline levels in biological samples (such as blood, urine, or tissues). For metabolite analysis, metabolomics approaches can be employed in conjunction with LC-MS/MS (liquid chromatography-mass spectrometry), allowing for simultaneous detection of multiple metabolites and obtaining a comprehensive metabolite profile. At MtoZ Biolabs, we offer an exceptional L-Norvaline Analysis Service, powered by our cutting-edge liquid chromatography-mass spectrometry (LC-MS) platform and a team of metabolomics experts. Our service provides a comprehensive and precise analysis of L-norvaline, ensuring high sensitivity and accuracy.

       

      Analysis Workflow 

       

      1838829213898625024-WorkflowofL-NorvalineAnalysisService.PNG

       

      Service Advantages

      • Extensive experience in various biological sample preparation techniques
      • Professional standard operating procedure
      • State-of-the-art facilities and equipment for precise analysis
      • Expert team with extensive experience in metabolomics
      • Comprehensive data analysis
      • Excellent customer service and after-service support

       

      Applications

      • Identification of new disease biomarkers
      • Improvement of disease diagnosis
      • Accelerating the discovery of next-generation therapeutics
      • Revealing new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. For each sample, a minimum of 3 bio-samples under the same conditions is required. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      To maintain stability, store the samples at -80°C.

       

      Note: Please provide detailed information on sample collection and handling. 

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on L-Norvaline

      4. Raw Data

      5. Custom Analysis Report

       

      With our L-norvaline analysis service, we are committed to enhancing your research and product development processes by delivering accurate and reliable results.

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