L-Gulonolactone Analysis Service

    L-Gulonolactone is a six-carbon sugar alcohol with the molecular formula C₆H₁₀O₆. Its chemical structure includes a lactone ring and is a reduced form of L-gulonic acid. L-Gulonolactone is primarily found in certain plants and animal tissues, especially in citrus fruits, some berries, and leafy green vegetables. It possesses antioxidant properties, capable of scavenging free radicals and protecting cells from oxidative stress. Furthermore, it plays a crucial role in the synthesis of vitamin C, which is essential for maintaining the antioxidant capacity and immune function of organisms. The content of L-gulonolactone in plants can serve as an important indicator of their antioxidant potential and nutritional value, which is vital for developing functional foods and dietary supplements. In living organisms, L-gulonolactone can be converted into ascorbic acid (vitamin C) and dehydroascorbic acid through a series of enzymatic reactions. These metabolites exhibit antioxidant and immune-regulating effects. Measuring the levels of L-gulonolactone and its metabolites (such as ascorbic acid) in biological systems can reflect the health status and metabolic state of the organism.

     

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    Figure 1. The Structure of L-Gulonolactone

     

    Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolic features and are widely used for the metabolic analysis of various compounds. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of L-gulonolactone. We ensure the accuracy of the quantification of L-gulonolactone and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you would like to learn more about our L-gulonolactone analysis services, please feel free to contact us, and we will be more than happy to assist you.

     

    Analysis Workflow

     

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    Service Advantages

    1. Experienced: MtoZ Biolabs has a professional research team and advanced technical equipment, capable of providing high-quality services and support to meet the specific needs of clients.

     

    2. Wide Applicability: It is suitable for various types of samples, including plants, animals, and biological fluids, making it applicable across a broad range of fields.

     

    3. High Throughput: Mass spectrometry technology can analyze multiple metabolites simultaneously in a short time, making it suitable for high-throughput analysis of large-scale samples.

     

    4. Targeted Compounds: Targeted metabolomics focuses on specific metabolites, effectively eliminating interference signals and enhancing the reliability of the data.

     

    5. Strong Detection Capability: Mass spectrometry technology can detect low concentrations of metabolites, making it suitable for analyzing rare or complex components in biological samples.

     

    Applications

    • Identifying new disease biomarkers
    • Improving disease diagnosis
    • Accelerating the discovery of novel therapeutics
    • Unraveling new insights into disease mechanisms

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Sample Preservation

    Store at -80°C to maintain stability.

     

    Note: Provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on L-Gulonolactone

    4. Raw Data

    5. Custom Analysis Report

     

    Our L-Gulonolactone Analysis Service is designed to support your research and product development efforts by delivering accurate and reliable results.

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