Isoallolithocholic Acid Analysis Service

Isoallolithocholic acid (IALCA) is a bile acid derivative metabolized from lithocholic acid, primarily found in bile. As a key intermediate in the bile acid metabolic pathway, IALCA is formed through enzymatic reactions in the liver and plays a crucial role in regulating bile acid balance and liver function. Fluctuations in IALCA levels are closely linked to various hepatobiliary diseases, such as cholestasis and cirrhosis. Therefore, accurately measuring IALCA levels is essential for understanding its metabolic role, assessing liver health, and conducting related research.

 

Figure 1. Molecular Structure of Isoallolithocholic Acid

 

MtoZ Biolabs offers Isoallolithocholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in IALCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of IALCA accurately.

 

2. High Specificity

Differentiates IALCA from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing IALCA and its related metabolites.

 

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

 

Applications

• Study bile acid metabolism pathways and regulatory mechanisms.
• Investigate the effects of drugs on bile acid metabolism to evaluate drug safety.
• Assist in the diagnosis of cholestasis, cirrhosis, and other hepatobiliary diseases.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Isoallolithocholic Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into IALCA's extensive physiological roles through top-tier analytical techniques and expert services.