IS Analysis Service
- Discovering new disease biomarkers
- Enhancing disease diagnosis
- Speeding up the discovery of innovative therapeutics
- Uncovering new insights into disease mechanisms
- Sample Types: Serum, plasma, urine, tissues, and other biological samples. We require at least three samples of the same condition for each type.
- Sample Volume: Animal tissue ≥ 100 mg, Plant tissue ≥ 200 mg, Serum/ Plasma ≥ 200 μL, Urine ≥ 2 mL.
- Sample Preservation: Samples should be stored at -80°C to maintain stability.
The main compounds of free IS include indole and indoxyl sulfate. Indole is produced by gut microbiota through the metabolism of tryptophan and is subsequently converted into indoxyl sulfate in the liver. These compounds exhibit significant biological activity in the human body, particularly in patients with chronic kidney disease, where indoxyl sulfate, as a uremic toxin, exacerbates kidney damage and is associated with cardiovascular diseases. The metabolites of free IS include indole and indole acetic acid, which play crucial roles in the interactions between gut microbiota and host metabolism. Analyzing the levels of free IS and its metabolites in plant and biological samples is important for assessing the impact of gut microbiota on host health and for understanding kidney damage and metabolic disorders. Additionally, studying these metabolites in plants can help elucidate their potential roles in plant growth, development, and stress responses.
Services at MtoZ Biolabs
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs offers an advanced LC-MS-based metabolomics platform for precise and comprehensive IS analysis. We specialize in quantifying IS and its metabolites accurately, as well as identifying metabolites comprehensively and precisely. If you require our IS analysis service, please feel free to contact us. We are committed to delivering high-quality analytical services and technical support.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform: MtoZ Biolabs established an advanced IS analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all IS analysis data, delivering clients a detailed and comprehensive data report.
4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.
Applications
Sample Submission Requirements
Note: Please provide detailed information on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on IS Analysis
4. Raw Data
5. Custom Analysis Report
Our IS analysis service aims to bolster your research and product development processes by providing accurate and reliable results. Please contact us for more information.
How to order?
