Hexosylceramide Analysis Service
- Accurate Quantification: Ensuring precise measurement of complex HexCers across various biological samples.
- Isomer Differentiation: Resolving and identifying challenging isomeric species using advanced mass spectrometry.
- Low-Abundance Detection: Detecting trace amounts of HexCers with high sensitivity.
- Comprehensive Profiling: Providing detailed lipid profiles for studying disease mechanisms and metabolic pathways.
- Basic research: Understand the role of hexosylceramide in cellular functions.
- Disease research: Investigate the correlation between hexosylceramide and various diseases.
- Drug development: Develop therapeutics targeting hexosylceramide.
- Animal tissue ≥ 100 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
- Cerebrospinal Fluid ≥ 2 mL
- Cell ≥ 1 x 10⁷ cells
Hexosylceramides (HexCers) are a significant class of glycosphingolipids that feature a ceramide backbone linked to a single hexose sugar, such as glucose or galactose. These lipids are integral components of cellular membranes and are involved in various biological processes, including cell signaling, apoptosis, and immune response regulation. Found predominantly in tissues such as the brain, skin, and immune cells, HexCers play vital roles in both normal physiological functions and disease mechanisms. Their structural diversity and tissue-specific distribution make them critical targets in lipidomics research.
Recent studies have highlighted HexCers' involvement in the development of neurodegenerative diseases such as Alzheimer's and Parkinson's, as well as their role in cancer and metabolic disorders. Aberrations in hexosylceramide metabolism are increasingly recognized as potential biomarkers for disease progression, making their precise analysis a priority for clinical and pharmaceutical research. However, due to their structural complexity and the presence of closely related isomers, HexCers are challenging to quantify and analyze without advanced analytical techniques.
Figure 1. The Structure of Hexosylceramide
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs provides a Hexosylceramide Analysis Service designed to address several key challenges faced by researchers:
Analysis Workflow
Service Advantages
1. Advance Analysis Platform
MtoZ Biolabs established an advanced hexosylceramide analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality
Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all hexosylceramide analysis service data providing clients with a comprehensive data report.
4. Fast Turnaround
The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is advised to prepare more than 3 biological replicates.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Hexosylceramide
4. Raw Data
5. Custom Analysis Report
For more information on our Hexosylceramide Analysis Service, please feel free to contact us at MtoZ Biolabs.
How to order?
