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    Guanosine Analysis Service

      Guanosine is a nucleoside composed of guanine attached to a ribose (ribofuranose) sugar via a β-N9-glycosidic bond. It plays a vital role in numerous biological processes, particularly in the synthesis of RNA, where it serves as one of the four essential building blocks. Beyond its role in RNA synthesis, guanosine and its phosphorylated derivatives (such as GMP, GDP, and GTP) are involved in a variety of cellular functions, including signal transduction, protein synthesis, and energy transfer.

       

      Structurally, guanosine features a purine base (guanine) linked to a ribose sugar. This molecular architecture allows guanosine to participate in hydrogen bonding and other interactions that are critical for the stability and function of RNA molecules. The dynamic balance of guanosine and its related compounds within the cell is tightly regulated, as disruptions in guanosine metabolism can lead to various pathophysiological conditions, including neurodegenerative diseases, cancer, and immune disorders.

       

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      Figure 1. The Structure of Guanosine

       

      MtoZ Biolabs offers a specialized Guanosine Analysis Service utilizing advanced mass spectrometry techniques to deliver accurate and sensitive detection of guanosine in various biological matrices. Our service is tailored to meet the needs of researchers and clinicians seeking to explore the complexities of guanosine metabolism and its implications in health and disease. 

       

      Analysis Workflow

       

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      Service Advantages

      • Expertise: With a team of experienced scientists and cutting-edge technology, we ensure accurate and reliable results.
      • Flexibility: We cater to a wide range of sample types and offer customized solutions to meet your specific research needs.
      • Comprehensive report: We provide a detailed report of the analysis, including methods, list of identified metabolites, and statistical analysis.

       

      Applications

      Guanosine analysis service can be applied in:

      • Biomarker discovery for various diseases
      • Drug metabolism studies
      • Pathway analysis in cellular processes

       

      Sample Submission Requirements

       

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      • Samples should be stored at -80℃ and shipped with dry ice.
      • We recommend providing at least 3 samples of similar conditions for each type of sample.
      • Other sample types, please contact us for more details.

       

      Deliverables

      1. Experimental Procedures

      2. Essential Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Guanosine

      4. Raw Data

      5. Custom Analysis Report

       

      For more information or to request our Guanosine Analysis Service, please contact us.

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