Guanine Analysis Service
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Guanine is a purine base with the chemical formula C₅H₅N₅O. Its structure consists of a bicyclic ring system that includes two nitrogen atoms and an amino group (-NH₂). As an important component of nucleic acids, guanine plays a crucial role in various biological processes. Guanine primarily originates from the metabolism of nucleotides, particularly from the degradation of DNA and RNA. It can also be synthesized through the de novo purine synthesis pathway, which converts simple molecules into purine bases. In biological systems, guanine has several important functions, including storing genetic information and mediating cellular signaling. In plants, the content of guanine can serve as an indicator of metabolic activity and overall health status. Certain environmental conditions may lead to variations in guanine levels, reflecting the plant's response to stress or developmental changes. In the body, guanine can be metabolized into other nucleotide derivatives, potentially helping to regulate the balance of nucleotide pools. Monitoring the levels of guanine and its metabolites in biological samples can provide valuable insights into cellular metabolism and health status, possibly indicating changes associated with diseases or metabolic disorders.
Figure 1. The Structure of Guanine
Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolic features and are widely used for the metabolic analysis of various compounds. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of guanine. We ensure the accuracy of the quantification of guanine and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you would like to learn more about our guanine analysis services, please feel free to contact us, and we will be more than happy to assist you.
Analysis Workflow
Service Advantages
1. Experienced: MtoZ Biolabs has a professional research team and advanced technical equipment, capable of providing high-quality services and support to meet the specific needs of clients.
2. Wide Applicability: It is suitable for various types of samples, including plants, animals, and biological fluids, making it applicable across a broad range of fields.
3. High Throughput: Mass spectrometry technology can analyze multiple metabolites simultaneously in a short time, making it suitable for high-throughput analysis of large-scale samples.
4. Targeted Compounds: Targeted metabolomics focuses on specific metabolites, effectively eliminating interference signals and enhancing the reliability of the data.
5. Strong Detection Capability: Mass spectrometry technology can detect low concentrations of metabolites, making it suitable for analyzing rare or complex components in biological samples.
Applications
1. Identification of novel disease biomarkers
2. Improvement of disease diagnosis
3. Acceleration of the discovery of new therapeutics
4. Revelation of new insights into disease mechanisms
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to ensure stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Guanine
4. Raw Data
5. Custom Analysis Report
Through our guanine analysis service, we aim to support your research and product development processes by furnishing you with accurate and reliable results.
How to order?
