Glycyrrhizic Acid Analysis Service

Glycyrrhizic acid (also referred to as glycyrrhizinic acid or glycyrrhizin) is the primary active compound extracted from the roots of Glycyrrhiza glabra. Classified as a saponin, it possesses a sweetness that is approximately 30 to 50 times greater than that of sucrose. Glycyrrhizic acid is widely utilized as a natural sweetener in the food, beverage, and confectionery industries. Additionally, due to its emulsifying and gelling properties, it is frequently employed in cosmetics. Beyond these applications, glycyrrhizic acid exhibits multiple biological activities, including anti-inflammatory, antiviral, and hepatoprotective effects. In Japan, it is notably used to mitigate the risk of liver cancer in patients with chronic hepatitis C.

 

 

Figure 1. Molecular Structure of Glycyrrhizic Acid

 

After oral ingestion, glycyrrhizic acid undergoes metabolic conversion in the intestines into 18β-glycyrrhetinic acid (Enoxolone), which is further metabolized in the liver and primarily excreted via bile, with a small proportion excreted through urine. Although glycyrrhizic acid offers significant health benefits, excessive consumption can result in adverse effects such as hypokalemia (low potassium levels) and elevated blood pressure. Therefore, accurate quantification of glycyrrhizic acid is essential to ensure its safety and efficacy in various applications.

 

MtoZ Biolabs offers Glycyrrhizic Acid Analysis Service using advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS). Our services deliver high sensitivity and precision, supporting its extensive use in pharmaceutical, food, and cosmetics sectors.

 

Analysis Workflow

 



 

Service Advantages

Why Choose MtoZ Biolabs?

1. Advance Analysis Platform: MtoZ Biolabs established an advanced targeted metabolomics analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all targeted metabolomics analysis data providing clients with a comprehensive data report.

4. Customized Service: Tailored to the specific research needs of our clients, we offer flexible experimental design and personalized data analysis to ensure the achievement of research goals to the fullest extent.

 

Sample Submission Requirements

 

 

 

Applications

1. Pharmaceutical Development and Evaluation: Glycyrrhizic acid is commonly integrated into formulations for its anti-inflammatory, antiviral, and hepatoprotective properties. Accurate quantification is essential for assessing its therapeutic potential and efficacy in clinical applications.

2. Food Additive Analysis: As a natural sweetener, glycyrrhizic acid is widely incorporated into foods, beverages, and confectionery products. Quantitative analysis ensures consistent glycyrrhizic acid levels and product quality.

3. Cosmetic Formulation: Glycyrrhizic acid's role as an emulsifier and gelling agent in cosmetics necessitates precise quantification to ensure its optimal concentration and performance within formulations.

4. Bioactivity Research: Given its antioxidant, anti-inflammatory, and immune-modulating properties, glycyrrhizic acid is a focal point in biological research. Quantitative analysis facilitates in-depth studies into its mechanisms of action and bioactivity.

 

Deliverables

What Could be Included in the Report?

1. Comprehensive Experimental Details

2. Materials, Instruments, and Methods

3. Total Ion Chromatogram & Quality Control Assessment

4. Data Analysis, Preprocessing, and Estimation

5. Bioinformatics Analysis

6. Raw Data Files

 

MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details!